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个人简介 Personal Profile         张文成，同济大学附属东方医院副研究员，硕士研究生导师，再生医学博士，上海市浦江人才。2007年毕业于西北农林科技大学生物科学专业，2012年于军事医学科学院获博士学位。以助理研究员在军事医学科学院工作两年后，2014-2018年赴美国北卡罗来纳大学教堂山分校（UNC-CH）Lola Reid教授实验室进行博士后训练，开展肝胆胰内胚层干细胞及其用于肝病和糖尿病治疗的研究。2019-2020年以研究助理分别在Reid教授实验室和Jian Liu教授实验室探索细胞外基质尤其硫酸乙酰肝素在内胚层干细胞和肿瘤干细胞命运调控中的作用和机制。2021年1月，进入同济大学附属东方医院再生医学研究所，同年获得“上海市浦江人才”资助。2022年12月，获上海市卫生系统副研究员。回国后主持国家级和省部级项目4项，近年来在Cell Stem Cell、Biomaterials、Matrix Biology、Journal of Hepatology、Hepatology等本领域国际核心期刊SCI收录论文20余篇，发表文章总影响因子178.838，其中第一、通讯（含共同）文章总影响因子126。参编（译）书籍中文、英文5部，其中包括肝病学领域的权威著作《The Liver：Biologyand Pathobiology (Sixth Edition)》；获批中国和美国国家发明专利14项，其中PCT专利3项。        主要研究方向包括：① 开展基于干细胞移植治疗终末期肝病的基础和应用研究，致力于解决以胆管树干细胞作为代表的种子细胞的体外扩增和体内再植中现存的问题，实现干细胞在终末期肝病治疗中的应用；②开展内胚层干细胞和人间充质干细胞的三维扩增，探究小分子化合物在谱系重编程和成体干细胞体外维持中的作用研究；③ 结合生物材料制定成体干细胞的体外扩增和干细胞向实质器官高效直接移植的策略；④开展糖胺聚糖中透明质酸和硫酸乙酰肝素在干细胞命运调控和纤维板层型肝癌治疗中的机制和应用研究。 研究方向Research Directions 干细胞与再生医学,内胚层细胞命运调控与异常,细胞外基质和糖生物学,组织工程与细胞治疗 2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。 报考意向 招生信息 生命科学与技术学院 硕士研究生 序号 专业 招生人数 年份 1 生物学 1 2024 报考意向 姓名: 手机号码： 邮箱： 毕业院校： 所学专业： 报考类型： 博士 硕士 个人简历*： 上传附件 支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg 成绩单*： 上传附件 支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg 其他材料： 上传附件 支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg 备注： 提交 科研项目 在研项目1. 国家自然科学基金面上项目，82270638，透明质酸调节MMP2-TIMP3平衡实现补片移植胆管树干细胞救治肝衰竭，2023.01-2026.12，52万，项目负责人，在研。2. 上海市2022年度“科技创新行动计划”自然科学基金项目，22ZR1451100，3-O硫酸乙酰肝素促进胆管树干细胞肝向分化成熟的机制和应用研究，2022.04-2025.03，20万，项目负责人，在研。3. 国家重点研发计划“干细胞及转化研究”重点专项，2020YFA0112603，基于微载体的肝前体细胞的规模化扩增，2020.10-2024.12，56.87万元，子课题负责人，在研。已完成项目1. 上海市浦江人才计划，21PJD059，胆管树干细胞补片移植治疗终末期肝病的应用研究，2021.10-2023.09，30万，项目负责人，结题。2. 纤维板层型肝癌基金项目（Fibrolamellar Cancer Foundation），纤维板层型肝癌类器官体的体外扩增（Fibrolamellar Carcinoma Organoids Expansion），2019.10-2020. 03，43万，参与（Research Associate），结题。3. Vesta Therapeutics项目研究基金，SRA-60486，肝脏胰腺干/祖细胞的高效移植策略（Grafting Strategies for Stem/progenitors for Liver and Pancreas），2018.07-2019.09，1172万，参与（Research Associate），结题。4. Vesta Therapeutics项目研究基金，SRA-60486，肝脏胰腺干/祖细胞的高效移植策略（Grafting Strategies for Stem/progenitors for Liver and Pancreas），2014.01-2018.12，2621万;  2015.01 -2015.12，591万 ；2016.01-2016.12，630万；2017.01-2018.12，951万，参与（Postdoctoral Associate），结题 。 研究成果 PUBLICATIONS(1) Shengwei Shen#,Wencheng Zhang#, Chang Xu#,Zhaoxuan Dong, Xicheng Wang, Changcheng Liu, Fengfeng Lu, Yihui Hu, Qinghe Tang,Yu Cheng*, Zhiying He*. Photoacoustic imaging-guidedmagnetotactic hepatocytes promote liver repopulation after transplantation. Chemical EngineeringJournal. 2024,150278.https://doi.org/10.1016/j.cej.2024.150278 (2) Miaomiao Chen, Guoxiu Wu, YanliLu, Shiwen Sun, Zhao Yu, Xin Pan, Wenjian Chen, Hongyu Xu, Hua Qiu, Weizhi He,Xiuhua Li, Xicheng Wang, Yi Luo, Yuan Du, Jialing Wu, Ke Wei, Wencheng Zhang, Zhongmin Liu, Zhiying He. Ap21-ATD Mouse Model for Monitoring and Eliminating Senescent Cells and ItsApplication in Liver Regeneration post Injury.Mol Ther. 2024 Apr 5:S15250016(24)00218-1. doi:10.1016/j.ymthe.2024.04.002.(3) Wencheng Zhang1#, Yongmei Xu2#, Xicheng Wang3#, Tsunekazu Oikawa, GuoweiSu, Eliane Wauthier, Guoxiu Wu, Praveen Sethupathy, Zhiying He3*, Jian Liu2*, and Lola M. Reid1*.Fibrolamellar Carcinomas–Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides. First or corresponding senior authors on 1 stem cell biology and matrix biology and chemistry. 2 glycosaminoglycan chemistry; 3 bioinformatics analyses. Matrix Biology. 2023.121:194–216.doi: 10.1016/j.matbio.2023.06.008.(4) Wencheng Zhang#, Yangyang Cui#, Yuan Du#, Yong Yang#, Ting Fang#, Fengfeng Lu, Weixia Kong, Canjun Xiao, Jun Shi, Lola M. Reid* and Zhiying He*.Liver cell therapies: cellular sources and grafting strategies. 2023. Frontiers of Medicine, 2023. https://doi.org/10.1007/s11684-023-1002-1.(5) Wencheng Zhang#, Xicheng Wang#, Giacomo Lanzoni, Eliane Wauthier, Sean Simpson, Jennifer Ashley Ezzell, Amanda Allen, Caroline Suitt, Jonah Krolik, Alexander Jhirad, Juan Dominguez-Bendala, Vincenzo Cardinale,Domenico Alvaro, Diletta Overi, Eugenio Gaudio, Praveen Sethupathy*, Guido Carpino*, Christopher Adin*, Jorge Piedrahita*, Kyle Mathews*, Zhiying He*,and Lola M. Reid*. A postnatal networkof co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans. npj Regenerative Medicine, 2023. 8(1):40. DOI : 10.1038/s41536-023-00303-5(6) Vincenzo Cardinale#, Guido Carpino#,Diletta Overi, Samira Safarikia,Wencheng Zhang, Matt Kanke, Antonio Franchitto, Daniele Costantini, OlgaRiccioni, Lorenzo Nevi, Michele Chiappetta, Paolo Onori, Yu-Han Hung, QuirinoLai, Ilaria Zizzari, Marianna Nuti, Massimo Rossi, Praveen Sethupathy, Lola M.Reid, Domenico Alvaro, Eugenio Gaudio. Human duodenal submucosal glands containa defined stem/progenitor subpopulation with liver-specific regenerativepotential. Journal of Hepatology 2022 Sep 8;S0168-8278(22)03068-9. http://doi:org/10.1016/j.jhep.2022.08.037(7) Yong Yang#,Wencheng Zhang#, Xicheng Wang, Jingxian Yang, Yangyang Cui,Haimeng Song, Weiping Li, Wei Li, Le Wu, Yao Du, Zhiying He*, Jun Shi*,Jiangnan Zhang*. A passage-dependent network for estimating the in vitrosenescence of mesenchymal stromal/stem cells using microarray, bulk and singlecell RNA sequencing. 2023. Frontiers in Cell and Developmental Biology, 2023. DOI: 10.3389/fcell.2023.998666(8) Wencheng Zhang, Eliane Wauthier, Giacomo Lanzoni, Homayoun Hani, Xianwen Yi, Diletta Overi, Lei Shi, Sean Simpson, Amanda Allen, Carolyn Suitt, Jennifer Ashley Ezzell, Domenico Alvaro, Vincenzo Cardinale, Eugenio Gaudio, Guido Carpino, Glenn Prestwich, Juan Dominguez-Bendala, David Gerber,Kyle Mathews, Jorge Piedrahita, Christopher Adin, Praveen Sethupathy, ZhiyingHe, and Lola M. Reid. Patch Grafting of Organoids of Stem/progenitors into Solid Organs Can Correct Genetic-Based Disease States. Biomaterials,  2022; 121647. http://doi.org/10.1016/j.biomaterials.2022.121647 . (9) Vincenzo Cardinale#, Guido Carpino#,Diletta Overi, Samira Safarikia, Wencheng Zhang, Matt Kanke, Antonio Franchitto, Daniele Costantini, Olga Riccioni, Lorenzo Nevi, Michele Chiappetta, Paolo Onori, Yu-Han Hung, QuirinoLai, Ilaria Zizzari, Marianna Nuti, Massimo Rossi, Praveen Sethupathy, Lola M.Reid, Domenico Alvaro, Eugenio Gaudio. Human duodenal submucosal glands containa defined stem/progenitor subpopulation with liver-specific regenerative potential. Journal of Hepatology, 2022 Sep 8;S0168-8278(22)03068-9. http://doi:org/10.1016/j.jhep.2022.08.037(10) Wenjian Chen#,  Wencheng Zhang#, Miaomiao Chen, Chao Yang, Ting Fang, Haifeng Wang, Lola M. Reid, He Zhiying. Applications and Mechanisms of CDK4/6 Inhibitor PD-0332991. Cell Oncol (Dordr), 2022 Sep 10， https://doi.org/10.1007/s13402-022-00714-4. (11) Wencheng Zhang, Guido Carpino, Kirk J. Wangensteen, Hexin Yan and Zhiying He. Editorial: Cell Therapy, Liver Diseases, and Regeneration. Frontiers in Cell and Developmental Biology, 2022 Sep 5;10:999305. http://doi:10.3389/fcell.2022.999305. (12) Wencheng Zhang, Yan-Ru Lou, Jianjun Zhou, Zhiying He. Editorial: Stem cells in Tissue Homeostasis and Disease. Frontiers in Cell and Developmental Biology, 2022;876060. http://doi:10.3389/fcell.2022.876060 . eCollection 2022. Mar 9. (13) Yuan Du#, Wencheng Zhang#, Hua Qiu#, Canjun Xiao, Jun Shi*, Lola M Reid*, Zhiying He*. Mouse Models of Liver Parenchyma Injuries and Regeneration. Frontiers in Cell and Developmental Biology, 2022; 3: 903740. http://doi:10.3389/fcell.2022.903740  eCollection 2022. May 3.(14) Wencheng Zhang, Giacomo Lanzoni, Homayoun Hani, Diletta Overi, Vincenzo Cardinale, Sean Simpson, Wendy Pitman, Amanda Allen, Xianwen Yi, Xicheng Wang, David Gerber, Glenn Prestwich, Oswaldo Lozoya, Eugenio Gaudio, Domenico Alvaro, Debra Tokaz, Juan Dominguez-Bendala,Christopher Adin, Jorge Piedrahita, Kyle Matthews, Praveen Sethupathy, Guido Carpino, Zhiying He, Eliane Wauthier and Lola M Reid. Patch Grafting,Strategies for Transplantation of Organoids into Solid Organs such as Liver. Biomaterials, 2021;121067. http://doi:10.1016/j.biomaterials.2021.121067 Epub2021 Aug 25. (15) Xicheng Wang#, Wencheng Zhang#, Yong Yang, Jiansong Wang, Hua Qiu, Lijun Liao, Tsunekazu Oikawa, Eliane Wauthier, Praveen Sethupathy*, Lola M Reid*, Zhongmin Liu *, ZhiyingHe*. A MicroRNA-Based Network Highlights the Crucial Role of PI3K/AKT Signaling for Human Hepatic Lineage Maturation. Frontiers in Cell and Developmental Biology, 2021; 9: 670059.Http://doi:10.3389/fcell.2021.670059.   eCollection 2021. Jun 1. (16) Fengfeng Lu#, Xin Pan#, Wencheng Zhang#, Xin Su, Yuying Gu, Hua Qiu, Shengwei Shen, Changcheng Liu, Wei Liu, Zhenzhen Zhan, Zhongmin Liu*, Zhiying He*. A Three-dimensional Imaging Method of Quantification and Localization for Dynamic Cell Tracking Post-transplantation. Frontiers in Cell and Developmental Biology, 2021 /fcell.2021.698795 http://doi:10.3389/fcell.2021.698795 .  eCollection 2021 Sep 7. (17) Fang Yan#, Yi Wang#, Wencheng Zhang, Mingyang Chang, ZhiyingHe, Jinbo Xu, Changzhen Shang, Tao Chen, Jiang Liu, Xin Wang, Xuetao Pei, Yunfang Wang. Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection. Hepatology, 2017;66(3):717-735. http://doi:10.1002/hep.29134 Epub 2017 Jul 27. (18) Haiyun Pei #, Chao Zhai #,Huilin Li, Fang Yan, Jinhua Qin, Hongfeng Yuan, Rui Zhang, Sihan Wang, Wencheng Zhang, Mingyang Chang, YunfangWang*, Xuetao Pei*. Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes. Stem Cell Res Ther, 2017;7;8(1):252. http://doi:10.1186/s13287-017-0703-2 . 2017 Nov 7. (19) Yunfang Wang#*, Jinhua Qin#, Shuyong Wang #, Wencheng Zhang #, Jialei Duan, Jing Zhang, Xin Wang, Fang Yan, Mingyang Chang, Xiaofang Liu, Bo Feng,Jiang Liu, Xuetao Pei*. Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules. Cell Stem Cell, 2016;6;19(4):449-461. Http://doi:10.1016/j.stem.2016.06.006 . Epub 2016 Jul 21.    (20) Jing Wang#, Shang Wang#, Wencheng Zhang, Tao Wang, Peiyao Li, Xiaoling Zhao, Chao Niu, Ying Liu, Xinxing Wang, Qiang Ma*. Proteomic profiling of heat acclimation in cerebrospinal fluid of rabbit. J Proteomics, 2016; 20; 144:113-122. http://doi:10.1016/j.jprot.2016.04.028 .  Epub 2016 May 18.  (21) Wencheng Zhang, Hailei Yao, Sihan Wang, Shuangshuang Shi,Yang Lv, Lijuan He, Xue Nan, Wen Yue, Yanhua Li*, Xuetao Pei*. Wnt3a is involved in the early stage of miPSC and mESC haemopoietic differentiation. Cell Biol International, 2012; 36(3): 267-71. Http://doi:10.1042/CBI20100766 . 2012 Mar 1.  BOOKS (CHAPTERS) (1) Lou, Y.-R., Zhang, W., Zhou, J., He,Z., eds. (2022).Stem cells in Tissues. Homeostasisand Disease. Lausanne: Frontiers Media SA.  Http://doi:10.3389/978-2-88974-801-3 ; ISSN1664-8714; ISBN 978-2-88974-801-3.(2) Wencheng Zhang, Amanda Allen, Eliane Wauthier, Xianwen Yi,Homayoun Hani, Praveen Sethupathy, David Gerber, Vincenzo Cardinale, Guido Carpino, Juan Dominguez‐Bendala, Giacomo Lanzoni, Domenico Alvaro, EugenioGaudio, Lola Reid. Stem Cell‐Fueled Maturational Lineages in Hepatic and Pancreatic Organogenesis. In The Liver(eds I.M. Arias, H.J. Alter, J.L. Boyer, D.E. Cohen, D.A. Shafritz, S.S.Thorgeirsson and A.W. Wolkoff).2020; 521-538. ISBN: 978-1-119-43682-9.(3) Jing Zhang, Yanhua Li, Xiaoyan Xie, Wencheng Zhang, Xuetao Pei. Regulation of Transcription Factors in Stem Cell Totipotency: The Role of Transcription Factors in iPS Cells, In Regenerative Medicine -Theory and Technology Science Press, 72-79 2010. ISBN978-7-03-027266-9.PATENTSPrimary patents have been filed for inventions regarding programmed endodermal stem cells (3), for methods and strategies for patch graft compositions and their uses (3), and for strategies by which to cause endodermal stem cell maturation to hepatocytes (1). Each of these primary patents has been filed in the USA, in China and to the Patent Cooperation Treaty (PCT).  The PCT governs patents for approximately 100 countries that are part of the patenttreaty.  One’s patent application is filed through the PCT in Europe and, if approved, can be honored in any of the countries with annual fees being paid. The patents noted below have been filed through the PCT and are being maintained in up to 30 countries for each patent.  In total 9 patents have been submitted to primary sources (USA and/or China) and 3 have been submitted to the PCT.  7 were granted as of June 1st, 2023. Each of those filed through the PCT have been arranged to be honored through up to 30 countries.  A. Patents on reprogrammed endodermal stem cells (3)(1)   Small molecule compound combination for reprogramming digestive tract derived epithelial cells to endodermal stem/progenitor cells, reprogramming method and application   WIPO (PCT)Pub. No.: WO2017206837A1     Pub. Date: 12/07/2017 Inventors: Yunfang Wang; Shuyong Wang; Wencheng Zhang; Jinhua Qin; Xuan Wang; Mingyang Chang; Fang Yan; Xuetao PeiIt has been granted by the United States(US11149253B2; 10/19/2021), China (201710389705.0;02/02/2021), Europe(EP2017805782; 11/17/2021) and other countries and regions. (2)   Method and application for reprogramming digestive tract source epithelial cells as endoderm stem/progenitor cell   China    Pub. No.: CN107142240A  Pub. Date: 09/08/2017Patent No.: ZL201710389711.6Granted Date: 01/29/2021 Inventors: Yunfang Wang; Shuyong Wang; Wencheng Zhang; Jinhua Qin (3) Passage method and application of endodermal stem / progenitor cells reprogrammed from digestive tract derived epithelial cells   ChinaPub. No.: CN113151157A   Pub. Date: 07/23/2021Granted Date: 09/05/2022Inventors: Yunfang Wang; Shuyong Wang; Wencheng Zhang; Jinhua Qin; Xuan Wang; Mingyang Chang; Fang Yan; Xuetao Pei B. Patent on stem cell maturation to hepatocytes (2)(1)   A biomarker ,dual omics kit and construction method for evaluating the maturity of liver lineage cells ChinaPub. No.: 2 CN113106160A Pub. Date: 04/12/2021Granted Date: 09/05/2021 Inventors: Zhiying He; Zhongmin Liu; Xicheng Wang; Wencheng Zhang (2) A processing method, system, and storage medium for biological sample information  ChinaPub. No.:202310414041.4Pub. Date: 04/18/2023Inventors: Zhiying He, Zhongmin Liu, Xicheng Wang, Wencheng Zhang, Guoxiu Wu, Yangyang Cui C. Patents on patch grafting compositions and strategies(3)(1)   Patch graft compositions for cell engraftment        U.S.A.     Pub. No.: US20180353652A1    Pub. Date: 12/13/2018Patent No.: US11129923B2Granted Date: 09/28/2021 Inventors: Lola M. Reid; Wencheng Zhang; Eliane Wauthier (2) Patch graft compositions for cell engraftment    WIPO(PCT) Pub. No.: WO2018231726A1     Pub. Date: 12/20/2018Inventors: Wencheng Zhang; Eliane Wauthier and Lola M. ReidIt has been filed in the United States (US20180353651A1; 12/13/2018;US20180353651A1;12/13/2018; US20180353653A1; 12/13/2018; US20180361027a1;12/20/2018; US20180361028A1;12/20/2018; US 20190388584A1;12/26/2019; US20190015556A1;01/17/2019), China (CN202080049127.6; 05/22/2020; CN111032090A;04/11/2020), Canada (CA3140912;05/22/2020), India (IN201937052705A;01/30/2020), Australia (AU2018282728;01/30/2020) and other countries and regions. (3) Patents on patch grafting methodsPatch grafting of stem / progenitor cells into solid organs     WIPO (PCT) Pub. No.: WO2020/242952A1    Pub. Date: 05/22/2022Inventors: Wencheng Zhang; Eliane Wauthier and Lola M. ReidIt has been filed in Australia (AU2020283472A1;01/20/2020),Canada (CA3140912; 05/22/2020), The Federative Republic of Brazil (BR112021023571A2;05/22/2020), and Argentina (AR112241A1; 05/22/2020). D. Patent on stemcell expansion systems (1)(1)   Expansion or passage system of biliary tree stem cells and its application ChinaPub. No.: 202310369365.0Pub. Date: 04/07/2023Inventors: Wencheng Zhang; Zhiying He; Yangyang CuiCONFERENCES/LECTURES(1) 07/07/2015- Poster Presentation at the Gordon Research Conference on Wound Healing and Tissue Regeneration, New London, USA.  Poster: Screening of Synthesized Defined Heparins for the Maintenance and Expansion of Hepatic Stem Cells.(2) 06/11/2016- Poster Presentation at the Gordon Research Conference on Proteoglycans held at the University of Andover Proctor. Poster: Patch Grafting Strategies for Transplantation of Stem/Progenitors into Liver.(3)  08/152017- Poster Presentation at the 11th International Hyaluronic Acid Conference held in Cleveland, Ohio, USA.  Poster: Patch Grafting Strategies for Transplantation of Stem/Progenitors into Internal Organs.(4)  06/08/2018-Invited Talk at the Gordon Research Seminar on Proteoglycans held at theUniversity of Andover Proctor.   Talk: Patch Grafting for Stem Cell Therapy for Liver and Pancreas.(5)  06/013/2018-Invited Talk at the Gordon Research Conference on Proteoglycans held at the University of Andover Proctor. Talk: Patch Grafting of Stem Cells for Liver Regeneration(6)  07/09/2019-Poster Presentation at the Gordon Research Conference on Wound Healing and Tissue Regeneration, New London, USA. Poster: Patch Grafting of Stem/Progenitor Cells into Solid Organs(7)  08/17/2020-invited lecture in Chinese at "Discovery Forum" of Regenerative Medicine Research Institute of Shanghai East Hospital. Lecture: Stem cell-based therapy for Liver Diseases.(8) 12/15/2020-invited to give lecture in English in the Sipping Science Society Salon in Shanghai. Lecture: Liver la Vida Loca: Live(r) it up with Liver Stem Cells(9) 04/01/2021- invited to give English science lecture to G11,12 students in Shanghai United International School. Lecture: Stem Cells for Liver Regeneration: What to Choose and How to Give?(10) 10/24/2021- invited Talk at the 4th World Cell Therapy and Regenerative Medicine Conference held at Taizhou,Jiangsu, China. Talk: Strategies for Patch Grafting of Organoids of Biliary Tree-derived Hepato/Pancreatic Stem/Progenitors into Liver and Pancreas(11) 11/26/2021- Talk at the 8th Young Scholars Forum 2021, Northwest Agricultural and Forestry University (virtual): Using Biliary Tree Stem Cell Organoids for the Treatment of Hepatic and Pancreatic Dysfunctions via Patch Grafting Strategies (12) Adam Francisco, Jine Li, Alaa Farghili, Matt Kanke, Bo Shui, Wencheng Zhang, Paul Soloway, Zhangjie Wang, Lola Reid, Praveen Sethupathy. Chemical, molecular, and single cell analysis reveal chondroitin sulfate proteoglycan aberrancy in fibrolamellar carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; CancerRes 2022;82(12_Suppl): Abstract nr 3830. (13) 02/18/2023-"Cell Therapy - China Innovation" Cell Therapy, Research and Application Innovation Forum,Zhangjiang, Shanghai, organizer/conference secretary (14) 03/23/2023-invited talk at the 7th Edition of International Webinar on Aging And Rehabilitation. Talk: Patch Grading of Biliary Tree Stem Cells for Liver Diseases and Diabetes. (15) 04/10/2023-04/14/2023, 2023 National Academic Conference of the Chinese Society of Cell Biology · Suzhou. Poster: Patch Grafting, Strategies for Delivery Stem Cell Organoids into Solid Organs.(16) 11/17-11/20/2023, The 12th InternationalConference on Biomedical Engineering and Biotechnology (ICBEB 2023), Macao, China. Invited talk: Patch Grafting of Stem Cell Organoids into the Liver and Pancreas to Rescue the Diseases States.TEACHING/COURSES(1) 2020-fall semester, Stem Cells and Liver Regeneration, course for PhD students, 4 hours(2) 2021-spring semester, Stem Cells and Liver Regeneration, course for PhD students, 4 hours(3)  2021-summer semester, Stem Cells and Liver Regeneration, lecture for undergraduate students in Biology and Bioinformatics, 0.5 hours(4) 2021-fall semester, Liver Regeneration, lecture for PhD students in Life Science 2 hours(5) 2021-fall semester, Cell Types in Liver and Their Application in Liver Regeneration, lecture for PhD students, 0.5 hours(6) 2022-fall semester, Cell Engineering, lecture for Medical School students, 4 hours(7) 2022-fall semester, Stem Cell and Tissue Engineering in Liver Repair, lecture for Medical School students, 4 hours(8) 2022-fall semester, Frontier of Biology: Stem Cells and Liver Regeneration,  course for PhD students, 2 hoursAWARDS(1)  Wencheng Zhang. Patch Grafting Technology for the Efficient Stem Cell Engraftment intothe Liver, Bronze Award in the35th Shanghai Excellent Invention Award, January 2024(2)  YangYang, Zhiying He, Wencheng Zhang, Xicheng Wang, Mingyang Xu, Yuting Li.A method for long-term cultivation and expansion of mature hepatocytes invitro, Third Prize of Pudong Employee Science and Technology InnovationAward in 2023, December 2023(3)  XichengWang, Wencheng Zhang, Ting Fang, Chao Yang, Mingyang Xu. Biomarkers,dual omics kits, and construction methods for evaluating the maturity of liverlineage cells. Bronze Award inthe 2023 Higher Education Invention Selection Competition, May 2023(4)  Wencheng Zhang. Patch Grafting Technology that Can Achieve Efficient Stem CellEngraftment into the Liver, won theSecond Prize of Pudong Staff's Scientific and Technological Innovation in 2022, December 2022 学术任职 （1）2024年至现在中国中西医结合学会业委员会委员（2）2024年至现在《医学参考报干细胞与再生医学专刊》青年编委（3）2023年至现在 国家自然科学基金委评议人（4）2023年至现在 中国细胞生物学学会干细胞研究与应用分会青年委员（5）2022年至现在 获上海市卫健委副研究员职称（6）2021年至现在 上海市科学技术委员会项目评审专家（7）2021年至现在 中国细胞生物学学会Chinese Science for Cell Biology会员（8）2021年至现在 学术期刊Life Research、Medical Data Mining杂志编委（9）2020年至现在 国际学术期刊Frontiers in Cell and Developmental Biology客座副主编（10）2020年至现在 中国整形美容协会干细胞研究与应用分会青年工作委员会委员（11）2020年至现在 上海干细胞转化医学工程技术研究中心科研秘书（12）2019年至现在 美国纤维板层型肝癌（FLC）研究基金会成员（13）2019年-2020年 美国肝病协会American Association of Liver Diseases(AASLD)会员（14）2019年-2020年 美国细胞生物学协会American Society for Cell Biology (ASCB)会员（15）2018年至现在 Hepatology、Frontiers of Medicine、Tissue Engineering、Int Immunopharmacology、Pharmaceutics、Diagnostics、Current Oncology、Journal of Clinical Medicine、Life审稿人 学生信息 研究生 宋锦佳 学生信息 当前位置：教师主页 > 学生信息 入学日期 所学专业 学号 学位 招生信息 当前位置：教师主页 > 招生信息 招生学院 招生专业 研究方向 招生人数 推免人数 考试方式 招生类别 招生年份