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更新日期：2018年8月30日 姓 名 陈谷 性 别 女 出生年月 1973年12月 籍贯 广东澄海市 民 族 汉族 政治面貌 九三学社社员 最后学历 博士研究生 最后学位 哲学博士 技术职称 教授 导师类别 博、硕导 行政职务 系副主任 Email chengu@scut.edu.cn 工作单位 食品科学与工程学院 邮政编码 通讯地址 13号楼 单位电话 个人简介 运用多组学技术，研究与开发功能食品与营养因子、发酵食品，研究微藻胁迫响应与信号转导机制。近5年发表SCI论文30余篇。第一或通讯作者论文在Biotechnology for Biofuels, Journal of Agricultural and Food Chemistry, Food Research International 等杂志发表。培养校优秀硕士2名。承担或参与国家自然科学基金面上项目、中国科学技术部863项目、中国科学技术部973项目、广东省科技计划项目及企业横向等课题十余项。 工作经历 1、2007.3-至今, 华南理工大学, 食品科学与工程学院2、2011.11-2012.11, 康奈尔大学, 食品系, 访问学者3、2004.9-2006.12, 香港科技大学, 生物系, 高级研究助理4、1998.7-2000.8, 中山大学, 生命科学学院, 讲师 教育经历 1、2000.8–2004.8, 香港科技大学, 生物学, 博士2、1995.9–1998.7, 中山大学, 遗传学, 硕士3、1991.9–1995.7, 中山大学, 生物化学, 学士 获奖、荣誉称号 获评华南理工大学2017年度学生科技创新优秀指导教师奖一等奖，获评2014-2015 学年度本科教学优秀一等奖 ，2013-2014、2011-2012 、2010-2011学年度本科教学优秀二等奖 ，2013-2014 学年度春花青年教师优秀教学三等奖 。 社会、学会及学术兼职 美国食品科学技术协会（IFT-Institute of Food Technologists) 会员，美国植物生理学会会员，中华吟诵协会会员。 研究领域 功能食品与营养因子的研究与开发；发酵食品的组学研究和开发应用、微藻胁迫响应与信号转导机制研究与开发应用。 科研项目 1、国家自然科学基金面上项目，31871766，基于多组学技术的广陈皮特征风味组分及其陈化微生物代谢机制研究2、广东省公益研究与能力建设专项资金项目，2015A020209029，广陈皮陈化过程特征代谢物鉴定分析和加速广陈皮陈化的新技术研究与示范。3、广州市科技创新委员会项目，201609010068，合成生物学与生物多样性-系列微电影推介与研讨活动。4、广东省公益研究与能力建设专项资金项目，2015B020202005，抗枯萎病香蕉品种选育、抗病基因组测序、繁殖及配套栽培技术研究。5、国家自然科学基金面上项目，31370383，CO2驱动胶球藻积累甘油三酯的脂组学变化及其机理研究。6、国家自然科学基金面上项目，31270085，蓝细菌集胞藻6803中S2P蛋白酶介导级联信号转导参与胁迫响应的机制研究。7、国家高技术研究发展计划（863）项目子课题，2013AA065802，利用微藻清洁制备生物燃料关键技术。8、国家重点基础研究发展计划（973）项目子课题，2011CB200901，能源微藻组学研究及生物标志物分子鉴定。9、华南理工大学中央高校基本科研业务费资助项目，SCUT2009ZM0006，集胞藻PCC6803中EGY同源蛋白酶切底物或相互作用蛋白的分离鉴定。10、国家自然科学基金青年科学基金项目，30800609，集胞藻6803中蛋白酶EGY1同源蛋白的鉴定及其基因表达调控与功能分析。 发表论文 1. 雷忠华; 陈聪聪; 陈谷*, 基于宏基因组和宏转录组的发酵食品微生物研究进展. [J] 食品科学 2018, 39, 330-3372. Zhu, B. J.#; Chen, G.#; Cao, X. P. et al., Molecular characterization of CO2 sequestration and assimilation in microalgae and its biotechnological applications. [J] Bioresource Technology 2017, 244, 1207-1215. doi:10.1016/j.biortech.2017.05.1993. Wang, H.; Wang, J.; Qiu, C.; Ye, Y.; Guo, X.; Chen, G.; Li, T.; Wang, Y.; Fu, X.; Liu, R. H., Comparison of phytochemical profiles and health benefits in fiber and oil flaxseeds (Linum usitatissimum L.). [J] Food Chemistry 2017, 214, 227-233. doi:10.1016/j.foodchem.2016.07.0754. Lin, S.; Yang, L.; Gu, C.; Li, B.; Chen, D.; Li, L.; Xu, Z., Pathogenic features and characteristics of food borne pathogens biofilm: Biomass, viability and matrix. [J] Microb Pathog 2017. doi:10.1016/j.micpath.2017.08.0055. Li, F. H.; Zhang, B.; Chen, G.*; Fu, X., The novel contributors of anti-diabetic potential in mulberry polyphenols revealed by UHPLC-HR-ESI-TOF-MS/MS. [J] Food Research International 2017, 100, 873-884. doi:10.1016/j.foodres.2017.06.0526. Li, F. H.; Zhang, B.; Chen, G.*; Fu, X., Analysis of solvent effects on polyphenols profile, antiproliferative and antioxidant activities of mulberry (Morus alba L.) extracts. [J] International Journal of Food Science and Technology 2017, 52, 1690-1698. doi:10.1111/ijfs.134437. Li, F. H.; Chen, G.*; Zhang, B.; Fu, X., Current applications and new opportunities for the thermal and non-thermal processing technologies to generate berry product or extracts with high nutraceutical contents. [J] Food Research International 2017, 100, 19-30. doi:10.1016/j.foodres.2017.08.0358. Chen, G.*; Chen, C. C.; Lei, Z. H., Meta-omics insights in the microbial community profiling and functional characterization of fermented foods. [J] Trends in Food Science & Technology 2017, 65, 23-31. doi:10.1016/j.tifs.2017.05.0629. Wang, H.; Wang, J.; Guo, X.; Brennan, C. S.; Li, T.; Fu, X.; Chen, G.; Liu, R. H., Effect of germination on lignan biosynthesis, and antioxidant and antiproliferative activities in flaxseed (Linum usitatissimum L.). [J] Food Chemistry 2016, 205, 170-177. doi:10.1016/j.foodchem.2016.03.00110. Wang, H.; Chen, G.*; Guo, X.; Abbasi, A. M.; Liu, R., Influence of the stage of ripeness on the phytochemical profiles, antioxidant and antiproliferative activities in different parts of Citrus reticulata Blanco cv. Chachiensis. [J] LWT - Food Science and Technology 2016, 69, 67-7511. Wang, H.; Chen, G.*; Fu, X.; Liu, R. H., Effects of aging on the phytochemical profile and antioxidative activity of Pericarpium Citri Reticulatae 'Chachiensis'. [J] Rsc Advances 2016, 6, 105272-105281. doi:10.1039/c6ra22082g12. Peng, H.; Wei, D.; Chen, G.*; Chen, F., Transcriptome analysis reveals global regulation in response to CO2 supplementation in oleaginous microalga Coccomyxa subellipsoidea C-169. [J] Biotechnol Biofuels 2016, 9, 151. doi:10.1186/s13068-016-0571-513. Lv, N.; Chen, J.-h.; Wei, D.; Chen, F.; Chen, G., Global metabolic regulation of the snow alga Chlamydomonas nivalis in response to nitrate or phosphate deprivation by a metabolome profile analysis. [J] Int J Mol Sci 2016, 17, 69414. Li, F.; Chen, G.*; Fu, X., Comparison of effect of gear juicer and colloid mill on microstructure, polyphenols profile, and bioactivities of Mulberry (Morus indica L.). [J] Food and Bioprocess Technology 2016, 9, 1233-1245. doi:10.1016/j.lwt.2016.01.02115. Guo, R.; Fu, X.; Chen, J.; Zhou, L.; Chen, G.*, Preparation and Characterization of Microemulsions of Myricetin for Improving Its Antiproliferative and Antioxidative Activities and Oral Bioavailability. [J] J Agric Food Chem 2016, 64, 6286-6294. doi:10.1021/acs.jafc.6b0218416. Wang, H.; Qiu, C. S.; Abbasi, A. M.; Chen, G.; You, L. J.; Li, T.; Fu, X.; Wang, Y. F.; Guo, X. B.; Liu, R. H., Effect of germination on vitamin C, phenolic compounds and antioxidant activity in flaxseed (Linum usitatissimum L.). [J] International Journal of Food Science and Technology 2015, 50, 2545-2553. doi:10.1111/ijfs.1292217. Peng, H.; Wei, D.; Chen, F.; Chen, G., Regulation of carbon metabolic fluxes in response to CO2 supplementation in phototrophic Chlorella vulgaris: a cytomic and biochemical study. [J] Journal of Applied phycology 2015, 1-9. doi:10.1007/s10811-015-0542-418. Ding, Q. L.; Chen, G.*; Wang, Y. L.; Wei, D., Identification of Specific Variations in a Non-Motile Strain of Cyanobacterium Synechocystis sp PCC 6803 Originated from ATCC 27184 by Whole Genome Resequencing. [J] Int J Mol Sci 2015, 16, 24081-24093. doi:10.3390/ijms16102408119. Chen, Y.; Chen, G.*; Fu, X.; Liu, R., Phytochemical Profiles and Antioxidant Activity of Different Varieties of Adinandra Tea (Adinandra Jack). [J] J Agric Food Chem 2015, 63, 169-176. doi:10.1021/jf503700v20. Chen, J. H.; Liu, X. G.; Wei, D.; Chen, G., High yields of fatty acid and neutral lipid production from cassava bagasse hydrolysate (CBH) by heterotrophic Chlorella protothecoides. [J] Bioresource Technology 2015, 191, 281-290. doi:10.1016/j.biortech.2015.04.11621. Wang, H.; Chen, G.*; Ren, D.; Yang, S. T., Hypolipidemic Activity of Okra is Mediated Through Inhibition of Lipogenesis and Upregulation of Cholesterol Degradation. [J] Phytotherapy Research 2014, 28, 268-273. doi:Doi 10.1002/Ptr.499822. Lei, H.; Chen, G.*; Wang, Y.; Ding, Q.; Wei, D., Sll0528, a Site-2-Protease, Is Critically Involved in Cold, Salt and Hyperosmotic Stress Acclimation of Cyanobacterium Synechocystis sp. PCC 6803. [J] Int J Mol Sci 2014, 15, 22678-22693. doi:10.3390/ijms15122267823. Fei, Y. T.; Liu, D. M.; Luo, T. H.; Chen, G.; Wu, H.; Li, L.; Yu, Y. G., Molecular characterization of Lactobacillus plantarum DMDL 9010, a strain with efficient nitrite degradation capacity. [J] PLoS One 2014, 9, e113792. doi:10.1371/journal.pone.011379224. Chen, G.*; Wang, H.; Zhang, X.; Yang, S. T., Nutraceuticals and functional foods in the management of hyperlipidemia. [J] Crit Rev Food Sci Nutr 2014, 54, 1180-201. doi:10.1080/10408398.2011.62935425. 秦春燕; 陈谷*, 集胞藻PCC6803中S2P蛋白酶假定底物的体外诱导表达及纯化. [J] 食品科学 2013, 34, 114-12026. Zhang Xu，Chen Gu *，Qin Chunyan，Wang Yuling，Wei Dong. Slr0643, an S2P homologue, is essential for acid acclimation in the cyanobacterium Synechocystis sp PCC6803, Microbiology-SGM，2012，158：2765-278027. Chen Gu*，Law Kenny，Ho Percy，Zhang Xu，Li Ning. EGY2, a chloroplast membrane metalloprotease, plays a role in hypocotyl elongation in Arabidopsis，Molecular Biology Reports，2012，39（3）：2147-215528. Li Yuqin，Zhang Bochao，Wang Xiaoqin，Yan Huidan，Chen Gu，Zhang Xuewu*. Proteomic analysis of apoptosis induction in human lung cancer cells by recombinant MVL，Amino Acids，2011，41（4）：923-93229. Li Yuqin，Liao Xiaoxia，Chen Gu，Yap Yeeleng，Zhang Xuewu*. Cloning, Expression and Purification of Microcystis viridis Lectin in Escherichia coli，Molecular Biotechnology，2011，47（2）：105-11030. Chen Gu*，Zhang Xu. New insights into S2P signaling cascades: Regulation, variation, and conservation，Protein Science，2010，19（11）：2015-203031. Shao Jun-Li，Long Yue-Sheng，Chen Gu，Xie Jun，Xu Zeng-Fu*，The reversed terminator of octopine synthase gene on the Agrobacterium Ti plasmid has a weak promoter activity in prokaryotes，Molecular Biology Reports，2010，37（5）：2157-216232. Huang GuanHua，Chen Feng，Wei Dong，Zhang XueWu，Chen Gu. Biodiesel production by microalgal biotechnology，Applied Energy，2010，87（1）：38-4633. Huang G. H.,Chen G., Chen F. Rapid screening method for lipid production in alga based on Nile red fluorescence. Biomass Bioenerg 2009, 33 (10):1386-139234. Wei AL.,Zhang XW.,Wei D.,Chen G.,Wu QY., Yang ST. Effects of cassava starch hydrolysate on cell growth and lipid accumulation of the heterotrophic microalgae Chlorella protothecoides. J Ind Microbiol Biot 2009, 36 (11):1383-138935. Li YQ, Zhang XW, Chen G, Wei D, Chen F. Algal lectins for potential prevention of HIV transmission. Current Medicinal Chemistry 2008, 15(11):1096-110436. Zhang XW, Yap YL, Wei D, Chen G, Chen F. Novel omics technologies in nutrition research. Biotechnology Advances 2008, 26(2):169-17637. Guo D, Gao XR, Li H, Zhang T, Chen G, Huang PB, An LJ, Li N. EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls. Plant Molecular Biology 2008, 66(4):345-36038. Chen G, Bi YR, Li N. EGY1 encodes a membrane-associated and ATP-independent metalloprotease that is required for chloroplast development. Plant Journal 2005, 41(3):364-37539. Chen G, Wang XL, Wong WS, Liu XD, Xia B, Li N. Application of 3 ' untranslated region (UTR) sequence-based amplified polymorphism analysis in the rapid authentication of Radix astragali. Journal of Agricultural and Food Chemistry 2005, 53(22):8551-855640. Chen, G.*, Ye, C.M., Huang, J.C., Yu, M., and Li, B.J.. Cloning of the papaya ringspot virus (PRSV) replicase gene and generation of PRSV-resistant papayas through the introduction of the PRSV replicase gene. Plant Cell Reports. (2001) 20:272-277. 出版专著和教材 1、Chen Gu，Zhang Xuewu. Proteomics in Food Biotechnology，Food Science in Omic Technologies Era, Noureddine BENKEBLIA, John Wiley & Sons Inc. Publication, pp 99-118, USA, 2012. (学术专著)2、Chen Gu，Zhang Xuewu，Yang Shang-tian. Genomics in Cancer Biomarker Discovery，Omics Technologies in Cancer Biomarker Discovery, Zhang Xuewu, Landes Bioscience, pp 1-21, USA, 2011. (学术专著) 科研创新 1、陈谷，王宏，一种含酶与陈皮提取物的漱口水及其制备方法，2017.12.01，中国，ZL201410425062.7 (发明专利)2、陈谷，王宏，一种含酶与陈皮提取物的假牙护理液及其制备方法，2017.8.25，中国，ZL201410424736.1 (发明专利)3、陈谷，王宏，川陈皮素的应用，2018.04.13，中国，ZL201510520595.8 (发明专利) 教学活动 开设本科生及研究生《食品生物化学》、《生物化学》、《生物化学与分子生物学基础》、《功能食品与营养因子》和《分子生物学》等理论及实验课程教学。主讲全英课程《食品生物化学》和《生物化学与分子生物学基础》，学科前沿课程《多组学技术在食品科学与工程的应用与发展动态》等。 指导学生情况 培养校优秀硕士生2名，指导本科生在国际遗传工程机器竞赛(iGEM)获得金奖。