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更新日期：2022年10月12日 姓 名 邵丹 性 别 男 出生年月 籍贯 民 族 政治面貌 最后学历 最后学位 技术职称 研究员 导师类别 博导 行政职务 Email 工作单位 邮政编码 通讯地址 单位电话 个人简介 邵丹博士2010年本科毕业于四川大学华西药学院，2015年于吉林大学获药理学博士学位，后进入美国哥伦比亚大学（Columbia University）生物医学工程系从事博士后研究工作，师从美国工程院、医学院和发明家科学院院士Kam W. Leong教授。2019年9月加入华南理工大学医学院/生命科学研究院并组建生物活性与仿生材料课题组，致力于生物材料的开发及其在炎症性疾病诊治领域的研究。近年来共发表SCI论文80余篇，其中以第一或通讯作者发表SCI论文40余篇，包括Nat. Rev. Mater., Sci. Adv. (2篇), Adv. Mater. (2篇), Mater. Today, Adv. Funct. Mater. (2篇), Adv. Sci. (3篇), ACS Nano, Sig. Transduct. Target Ther., Small, Biomaterials (5篇)和Theranostics (2篇)等国内外高水平期刊, 其中8篇（曾）入围ESI高被引论文，9篇被选为期刊封面/内封面，总引用次数超3000次，Hindex=33（Google Scholar）；受邀担任中国化学快报英文版青年编委以及Front. Bioeng. Biotech., Int. J. Mol. Sci., Molecules和Adv. Polym. Technol.客座编辑，并担任Adv. Mater., Adv. Sci. Adv. Funct. Mater., Biomaterials, ACS Nano, Nano Lett., Small, Bioactive Mater., Biosens. Bioelectron., Chem. Eng. J., Theranostics, Adv. Healthc. Mater., ACS Appl. Mater. Interfaces, Acta Biomater.等多个高水平期刊审稿人。主持国家自然科学基金项目3项，申请中国发明专利8项。 工作经历 2019.09-至今，华南理工大学，医学院、生命科学研究院，特聘研究员2016.03-2019.08，美国哥伦比亚大学（Columbia University）生物医学工程系，博士后研究员2015.07-2016.02，中国科学院苏州生物医学工程技术研究所，研究实习员 教育经历 2010.09-2015.06，吉林大学，基础医学院，药理学，博士2006.09-2010.06，四川大学，华西药学院，药学，学士 研究领域 针对炎症性疾病诊治中所面临的挑战和机遇，发展以可降解生物活性材料为基础且具有多重危险信号分子清除功能的免疫生物材料，并系统性研究免疫生物效应与材料设计之间的相互作用关系和机制，利用生物制造技术构筑具有降解能力强、清除效率高和安全性好的系列免疫生物活性材料，实现炎症性疾病高效安全的诊治及相关器件研发和转化。 发表论文 1. Tu Z, Zhong Y, Hu H, Shao D*, Haag R, Schirner M, Lee J, Sullenger B, Leong K*. Design of therapeutic biomaterials to control inflammation. Nature Reviews Materials. 2022, 1-18.（ESI高被引论文）2. Shi C, Dawulieti J, Shi F, Chao Y, Qian Q, Shi T, Wang L, Hu H, Sun M, Ren L, Chen F, Zhao Y, Liu F, Li M, Mu L, Liu D, Shao D*, Leong K*, She J*. A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease. Science Advances. 2022, 8: eabj2372. （ESI高被引论文）3. Yang Y, Chen F, Xu N, Yao Q, Wang Y, Xie X, Zhang F, Shao D*, Dong W, Fan J, Sun W*, Peng X. Red-Light-Triggered Self-Destructive Mesoporous Silica Nanoparticles for Cascade Amplifying Chemo-Photodynamic Therapy Favoring Antitumor Immune Responses. Biomaterials. 2022, 281: 121368. （ESI高被引论文）4. Yang C, Dawulieti J, Zhang K, Cheng C,Zhao Y, Hu H,Li M, Zhang M, Chen L, Leong K*, Shao D*. An Injectable Antibiotic Hydrogel that Scavenges Proinflammatory Factors for the Treatment of Severe Abdominal Trauma. Advanced Functional Materials. 2022, 32: 202111698.5. Tu Z, Zhu Y, Xiao Y, Che J, Shannon S, Zhang F, Li Z, Zhou J, Hu H, Ho T, Gao W, Shao D*, Leong K*. Scavenging tumor-derived small extracellular vesicles by functionalized 2D materials to inhibit tumor regrowth and metastasis following radiotherapy. Advanced Functional Materials. 2022, 202205663.6. Chen X, Shi T, Yang C*, Chen F, He X, Zhang K, Hu H, Cai L, Leong K*, Shao D*. Scalable Biomimetic SARS-CoV‑2 Nanovaccines with Robust Protective Immune Responses. Signal Transduction and Targeted Therapy. 2022, 7: 1-3.7. Peng J, Chen F*, Liu Y, Zhang F, Chao L, You Q, Yang D, Chang Z, Ge M, Li L, Wang Z, Mei Q, Shao D*, Chen M, Dong W*, Peng X. A light-driven dual-nanotransformer with deep tumor penetration for efficient chemo-immunotherapy. Theranostics. 2022, 12: 1756-1768. （内封面论文）8. Zhang K, Yang C*, Chen C, Shi C, Sun M, Hu H, Shi T, Chen X, He X, Zheng X, Li M, Shao D*. Bioactive Injectable Hydrogel Dressings for Bacteria Infected Diabetic Wound Healing: A “Pull-Push” Approach. ACS Applied Materials & Interfaces. 2022, 14, 26404. 9. Hu H, Yang C, Li M, Shao D*, Mao H, Leong K*. Flash technology-based self-assembly in nanoformulation: Fabrication to biomedical applications. Materials Today. 2021, 42: 99-116. 10. Hu H, Yang C, Zhang F, Li M, Tu Z, Mu L, Dawulieti J, Lao Y, Xiao Z, Yan H, Sun W, Shao D*, Leong K*. A Versatile and Robust Platform for the Scalable Manufacture of Biomimetic Nanovaccines. Advanced Science. 2021, 8：2002020.（内封面论文）11. Dawulieti J, Sun M, Zhao Y, Shao D*, Yan H, Lao Y, Hu H, Cui L, Lv X, Liu F, Chi C, Zhang Y, Li M, Zhang M, Tian H, Chen X, Leong K*, Chen L*. Treatment of Severe Sepsis with Nanoparticulate Cell-free DNA Scavengers. Science Advances. 2020, 6: eaay7148. 12. Shao D*, Zhang F, Chen F, Zheng X, Hu H, Yang C, Tu Z, Wang Z, Chang Z, Lu J, Li T, Zhang Y, Chen L, Dong W*, Leong K*. Biomimetic Diselenide-Bridged Mesoporous Organosilica Nanoparticles as an X-ray-Responsive Biodegradable Carrier for Chemo-Immunotherapy. Advanced Materials. 2020, 32: 2004385.（正封面论文）13. Wang Z, Zhang F, Shao D*, Chang Z, Wang L, Hu H, Zheng X, Li X, Chen F, Tu Z, Li M, Sun W*, Chen L, Dong W*. Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti-Metastatic Immunotherapy. Advanced Science. 2019, 6, 1901690.（ESI高被引论文，内封面论文）14. Yan H, Shao D*, Lao Y, Li M, Hu H, Leong K*. Engineering of Cell Membrane-based Nanotherapeutics to Target Inflammation. Advanced Science. 2019, 6: 1900605.（ESI高被引论文，正封面论文）15. Shao D, Li M, Wang Z, Zheng X, Lao Y, Chang Z, Zhang F, Lu M, Yue J, Hu H, Yan H, Chen L, Dong W*, Leong K*. Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery. Advanced Materials. 2018, 30: 1801198. （ESI高被引论文，正封面论文）16. Wang Z, Chang Z, Lu M, Shao D*, Yue J, Yang D, Zheng X, Li M, He K, Zhang M, Chen L, Dong W*. Shape-Controlled Magnetic Mesoporous Silica Nanoparticles for Magnetically-Mediated Suicide Gene Therapy of Hepatocellular Carcinoma. Biomaterials. 2018, 154: 147-157. （ESI高被引论文）