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个人经历 personal experience 工作经历 教育经历 2017.12-今                     西北工业大学生命学院                                          助理教授2013.07-2017.11            空军军医大学基础部/航空航天医学院                    博士后2017.12 - Present     Assistant Professor, School of Life Sciences, Northwestern Polytechnical University.2013.07-2017.11      Postdoc, Department of Aerospace Medicine/School of Basic Medical Sciences, Air Force Medical University (Fourth Military Medical University) 2006.09 - 2012.12          中国农业大学生物学院                               博士2002.09 - 2006.07          山东农业大学生命科学学院                        本科2006.09 - 2012.12    Ph.D. College of Biological Sciences, China Agricultural University.2002.09 - 2006.07    Bachelor, College of Life Sciences, Shandong Agricultural University.

教育教学

科学研究 Scientific Research 1.  国家自然科学基金面上项目：运动裨益房颤的线粒体机制：抑制琥珀酸堆积及其介导的琥珀酰化作用；批准号：32371164；起止年月：2014/01-2027/12；负责人2.  国家自然科学基金面上项目：心房钠尿肽在糖尿病促发心衰中的作用及机制；批准号：31871172；起止年月：2019/01-2022/12；负责人3.  国家自然科学基金青年项目：胰岛素促进心房钠尿肽分泌延缓缺血性心力衰竭的发展及机制；批准号：31500928；起止年月：2016/01-2018/12；负责人4.  空间站工程第二批舱内实(试)验项目；空间蛋白质分子组装及应用研究(子课题三：蛋白质晶体空间辐射损伤研究)；批准号:YYWT-0901-EXP-10；起止年月：2022/01-2023/12；子课题负责人5.  陕西省重点研发计划(一般项目)：白介素33对心房颤动的作用及机制研究；项目编号：2023-YBSF-600；起止年月：2023/01-2024/12；负责人6.  中国博士后科学基金：胰岛素促进mPTP糖基化修饰减轻心肌再灌注损伤及其机制；批准号：2014M562597；起止年月：2014/07-2016/07；负责人National Science Foundation of China (Grant number 32371164). 2024/01-2027/12.National Science Foundation of China (Grant number 31871172). 2019/01-2022/12.National Science Foundation of China (Grant number 31500928). 2016/01-2018/12.China Postdoctoral Science Foundation (Grant number 2014M562597).  2014/07-2016/07. Key Research and Development Project of Shaanxi Province  (Grant number 2023-YBSF-600).  2023/01-2024/12.

荣誉获奖

学术成果 Academic Achievements 1. Wang Y, Wang Q, Liu P, Jin L, Qin X*, Zheng Q*. Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning. Hereditas. 2023. 160: 34. 2.  Qin X#, Fu Y#, Fan J#, Liu B, Liu P, Zhang Y, Jiang T*, Zheng Q*. Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload. Journal of Pineal Research. 2023. 74(3):e12851.  (IF=12.081, 1区TOP)3. Zhang Y#, Gao F#, Gong H, Fu Y, Liu B, Qin X*, Zheng Q*. Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2023. 1869(4):166638. 4. Fu Y, Liu P, Jin L, Li Y, Zhang Y, Qin X*, Zheng Q*. Left bundle branch area pacing: A promising modality for cardiac resynchronization therapy. Frontiers in Cardiovascular Medicine. 2022. 9: 901046. 5. Qin X#, Zhang Y#, Zheng Q*. Metabolic Inflexibility as a Pathogenic Basis for Atrial Fibrillation. International Journal of Molecular Sciences. 2022. 23(15):8291.6. Qin X#, Liu B#, Gao F#, Hu Y, Chen Z, Xu J*, Zhang X*. Gluconolactone alleviates myocardial ischemia/reperfusion injury and arrhythmias via activating PKCε/ERK signaling.  Frontiers in Physiology. 2022. 13: 856699. 7. Zhang Y#, Fu Y#, Jiang T#, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X*, Zheng Q*. Enhancing fatty acids oxidation via L-carnitine attenuates obesity-related atrial fibrillation and structural remodeling by activating AMPK signaling and alleviating cardiac lipotoxicity. Frontiers in Pharmacology. 2021. 12:771940. 8. Fu Y, Jiang T, Sun H, Li T, Gao F, Li X, Qin X*, Zheng Q*. Necroptosis is required for atrial fibrillation and involved in aerobic exercise-conferred cardioprotection. Journal of Cellular and Molecular Medicine.2021. 25(17):8363-8375.9. Liu P, Sun H, Zhou X, Wang Q, Gao F, Fu Y, Li T, Wang Y, Li Y, Fan B, Li X, Jiang T, Qin X*, Zheng Q*. CXCL12/CXCR4 axis as a key mediator in atrial fibrillation via bioinformatics analysis and functional identification. Cell Death & Disease. 2021. 12(9):813. (IF=9.685；入围2022年中国心律失常领域十大原创研究)10. Jin L#, Gao F#, Jiang T#, Liu B, Li C, Qin X*, Zheng Q*. Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity. Biochemical and Biophysical Research Communications. 2021.558C:126-133.11. Liu P, Wang Q, Sun H, Qin X*, Zheng Q*. Left bundle branch pacing: Current knowledge and future prospects. Frontiers in Cardiovascular Medicine. 2021, 8:114.12. Chen Z#, Qin X#, Zhang X, Liu B, Chen M*. Upregulation of IL-4 signaling contributes to aerobic exercise-induced insulin sensitivity. Biochemical and Biophysical Research Communications. 2020, 525(3):662-66713. Qin X#, Chen Z*. Metabolic dependence of cyclosporine A on cell proliferation of human non-small cell lung cancer A549 cells and its implication in post-transplant malignancy. Oncology Reports. 2019, 41(5): 2997-3004.14. Hou Z#, Qin X#, Hu Y, Zhang X, Li G, Wu J, Li J, Sha J, Chen J, Wang L*, Gao F*. Long-term exercise-derived exosomal miR-342-5p: a novel exerkine for cardioprotection. Circulation Research. 2019,124(9): 1386-1400. (IF=23.213；连续四年为ESI高被引论文)15. Qin X#, Li X#, Liu C, Chen Z*. A novel mechanism of pre-transplant insulin resistance contributing to post-transplant complications: Cyclosporin A-induced O-GlcNAcylation. Biochemical and Biophysical Research Communications. 2017,492(2):172-177.16. Qin X, Chen Z, Li P, Liu G*. Crystallization and X-ray diffraction analysis of the CH domain of a cotton kinesin GhKCH2. Acta Crystallographica Section F. 2016, 72(3): 240-243.17. Wang B#, Qin X#, Wu J, Deng H, Li Y, Yang H, Chen Z, Liu G, Ren D*. Analysis of crystal structure of Arabidopsis MPK6 and generation of its mutants with higher activity. Scientific  Reports. 2016, 6: 25646. (解析出第一个植物MAPK晶体结构；AtMPK6；PDB code: 5CI6)18. Xu J#, Qin X#, Cai X, Yang L, Xing Y, Li J, Zhang L, Tang Y, Liu J, Zhang X, Gao F*. Mitochondrial jnk activation triggers autophagy and apoptosis and aggravates myocardial injury following ischemia/reperfusion. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2015;1852(2):262-270.19. Qin X, Chen Z, Xu T, Li P, Liu G. Crystallization and preliminary X-ray diffraction studies of the GhKCH2 motor domain: alteration of pH significantly improved the quality of the crystals. Acta Crystallographica Section F. 2012;68:798-801.

科学研究

学术成果

综合介绍