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郑芬芬 副教授 环境与化学工程学院 个人邮箱： zff1108@126.com 办公地点： 长山校区18栋环化学院206 通讯地址： 长山校区18栋环化学院206 邮政编码： 传真： 个人简介 郑芬芬，副教授，博士。2017年博士毕业于南京大学化学化工学院，获化学专业博士学位，现任职于江苏科技大学环境与化学工程学院。目前主持国家自然科学基金1项，江苏省自然科学基金1项。近年来，在Angew. Chem. Int. Ed (2篇)、ACS Nano、Chemical Science、Anal. Chem.、Biomaterials等国际高水平学术期刊共发表论文20余篇。获2019年省“双创博士”，2021校深蓝杰出人才。 研究方向 从事功能纳米材料的合成及应用。从事生命物质及小分子的分析检测及荧光成像研究。从事体外、细胞以及活体层面上的靶向药物输送研究。 教育经历 2020/01-至今        南京大学         化学               博士后2013/09-2017/08     南京大学         化学               理学博士2010/09-2013/06     安徽师范大学    分析化学             理学硕士2006/09-2010/06     安徽师范大学    化学教育              本科 课程教学 2019-2020-1 承担环境工程及新能源专业大一的《无机及分析化学》课程，48学时            承担高分子专业大一的《无机及分析化学》课程，48学时2019-2020-2 承担研究生课程《纳米分析化学》，32学时2020-2021-1 承担食品专业《无机及分析化学》课程，48学时        承担食品专业《无机及分析化学》实验课程，16学时        承担研究生课程《生命分析化学》，32学时 科研项目 （1）2019.01-2021.12，基于纳米界面DNA杂交链反应的单细胞内蛋白激酶分析研究，27万，国家自然科学基金青年基金，No.21804059，主持（2）2018.07-2021.06，DNA杂交链反应信号放大策略用于单细胞内蛋白激酶活性分析，20万，江苏省自然科学基金青年基金，主持（3）2020 中国博士后基金，主持（4）2019.3 南京大学生命分析化学重点实验室开放基金，5万，主持（5）2019省高层次创新创业人才引进专项资金，15万，主持（6）2020 江苏省博后基金，主持 专利成果 科研团队 获奖动态 教学随笔 论文著作 Ran Liu, Difei Jiang, Yangfang Yun, Zhe Feng, Fenfen Zheng*, Yu Xiang,* Huanhuan Fan, Jingjing Zhang*, Photoactivatable Engineering of CRISPR/Cas9-Inducible DNAzyme Probe for In Situ Imaging of Nuclear Zinc Ions, Angew. Chem. Int. Ed., 2024, DOI: 10.1002/anie.202315536.Ting Wang, Kai Jiang, Yifan Wang, Limei Xu, Yingqi Liu, Shiling Zhang, Weiwei Xiong, Yemei Wang, Fenfen Zheng*, Jun-Jie Zhu*, Prolonged near-infrared fluorescence imaging of microRNAs and proteases in vivo by aggregation-enhanced emission from DNA-AuNCs Nanomachines, Chemical Science, 2024, DOI: 10.1039/D3SC05887E.Kai Jiang, Zhifeng Guan, Yifan Wang, Jiamin Sun, Weiwei Xiong,Fenfen Zheng*, Yemei Wang*, Jun-Jie Zhu*, Cell-Derived N/P/S-Codoped Fluorescent Carbon Nanodots with Intrinsic Targeting Ability for Tumor-Specific Phototheranostics. Anal. Chem.2023, 95, 47, 17392-17399.Sun, J.; Jiang, K.; Wang, Y.; Liu, Y.; Wang, T.; Ding, S.; Zhang, X.; Xiong, W.; Zheng, F. *; Yang, H. *; Zhu, J. J. * Adv. Healthcare Mater. 2023,12, 2302016.Sun, X.; Liang, X.; Wang, Y.; Ma, P.; Xiong, W.; Qian, S.; Cui, Y.; Zhang, H.; Chen, X.; Tian, F.; Shi, Y.; Zheng, F.*; Li, L.* Biomaterials 2023, 301, 122263.Difei Jiang, Yifan Pan, Haiyang Yao, Jiamin Sun, Weiwei Xiong, Lingling Li, Fenfen Zheng,* Shasha Sun,*  Jun-Jie Zhu,* Synthesis of Renal-Clearable Multicolor Fluorescent Silicon Nanodots for Tumor Imaging and in VivoH2O2 Profiling, Anal. Chem.,2022,  94, 9074-9080.Jinzhu Zhang, Wei Hua, Xiaoye Zhou, Chen Zhou, Yemei Wang, Xianzhi Chai, Shasha Sun*, and Fenfen Zheng* Renal-Clearable Dye-Conjugated Silver Nanoparticles for in Vivo Plasma Biothiol Sensing Through Urinalysis, Sensors and Actuators: B. Chemical 365 (2022) 131908Zhoujia Liu, Peng Yan, Yixuan Bai, Zhiqian Zhang, Xiaogang Li, Weiwei Xiong*, Junhao Zhang, Aihua Yuan*, and Fenfen Zheng*  High synergetic transition metal phosphides@ nitrogen doped porous carbon nanosheets hybrids derived from silk fibroin and phytic acid self-assembly for ultra-high performance lithium storage. Journal of Alloys and Compounds, 2022,Accept.Fenfen Zheng, Tiantian Meng, Difei Jiang, Jiamin Sun, Haiyang Yao, Jun-Jie Zhu, and Qianhao Min*，Nanomediator–Effector Cascade Systems for Amplified Protein Kinase Activity Imaging and Phosphorylation-Induced Drug Release In Vivo，Angew. Chem. Int. Ed. 2021, 60, 21565–21574.Haiyang Yao, Difei Jiang, Gaoqiu Dong, Jiamin Sun, Shasha Sun, Lingling Li, Fenfen Zheng* and Weiwei Xiong *,Near infrared imaging of intracellular GSH by AuNCs@MnO2 coreshell nanoparticles based on absorption competition mechanism,Analyst,2021,146,5115-5123.Yang Han, Zhoujia Liu, Fenfen Zheng*, Yixuan Bai, Zhiqian Zhang, Xiaogang Li, Weiwei Xiong*, Junhao Zhang, Aihua Yuan*, Two-dimensional flower-like cobalt-porphyrin MOF/rGO composite anodes for high-performance Li-ion batteries.Journal of Alloys and Compounds, 2021, 881: 160531.Xue Mingliang, Mao Wei, Chen Jisen, Zheng Fenfen*, Chen Wenhui, Shen Wei*, Tang Sheng*, Application of Au or Ag nanomaterials for colorimetric detection of glucose, Analyst, 146 (2021) 6726-6740.Zhoujia Liu, Fenfen Zheng*, Weiwei Xiong*, Xiaogang Li, Aihua Yuan*, and Huan Pang*, Strategies to improve electrochemical performances of pristine metal organic frameworks-based electrodes for lithium/sodium-ion batteries, SmartMat, 2021, DOI: 10.1002/smm2.1064.Fenfen Zheng, Chen Wang, TiantianMeng, Yuqian Zhang, Penghui Zhang, Qi Shen, Yuchao Zhang, Junfeng Zhang, Jianxin Li, Qianhao Min,*Jiangning Chen*,andJun-Jie Zhu*. Outer Frame-Degradable Nanovehicles Featured with Near-Infrared Dual Luminescences for In Vivo Tracking of Protein Delivery in Cancer Therapy. ACS Nano, 2019, 13, 12577-12590.(IF：13.9)Zheng, F*.; Xiong, W.; Sun, S.; Zhang, P.; Zhu, J. J. Recent Advances in Drug Release Monitoring. Nanophotonics, 2019, 8, 391-413.（IF：6.014）Fenfen Zheng, Penghui Zhang, Yu Xi, Kaikai Huang, Qianhao Min*, and Jun-Jie Zhu*, Peptide-Mediated Core/Satellite/Shell Multifunctional Nanovehicles for Precise Imaging of Cathepsin B Activity and Dual-Enzyme Controlled Drug Release, NPG. Asia Materials, 2017, 9, e366. (IF：9.16)Fenfen Zheng, Penghui Zhang, Yu Xi, Jingjia Chen, Lingling Li*, and Jun-Jie Zhu*, Aptamer/Graphene Quantum Dots Nanocomposite CappedFluorescent Mesoporous Silica Nanoparticles for Intracellular DrugDelivery and Real-Time Monitoring of Drug Release, Anal. Chem.,2015, 87,11739−11745. (IF: 6.32)Fenfen Zheng, Penghui Zhang, Yu Xi, Xueqin Chen, Tiantian Meng, Kaikai Huang, Ling-LingLi*and Jun-Jie Zhu*, Hierarchical Nanocarrier for Precisely Regulating Therapeutic Process via Dual-Mode Controlled Drug Release in Target Tumor Cells,ACS Appl. Mater. Interfaces, 2017, 9, 36655−36664. (IF: 7.51)Weiwei Xiong*, Ziyi Zhang, Yutao Huang, Chenxin Xu, Jiajing Wu, Lingling Li, Fenfen Zheng,* Wu, Xingcai*, A microwave-assisted template-free route for large-scale synthesis of photoluminescent single crystal CsPbI3 nanotubes, CrysEngComm, 2020, 22, 623. 7/8 (通讯作者) SCI 二区Fenfen Zheng,Jian-Feng Wuand Guang-Chao Zhao*, Peptide–Quantum Dot Bioconjugates for Label-Free Trypsin Detection Based on the Exciton Energy Transfer, Anal. Methods,2012, 4, 3932–3936.(IF: 1.9)Rui Ban, Fenfen Zheng, Jianrong Zhang*, A Highly Sensitive Fluorescence Assay for 2,4,6-trinitrotoluene Using Amine-Capped Silicon Quantum Dots as a Probe, Anal. Methods, 2015, 7, 1732–1737.Jingjing Xue,Ziyi Zhang,Fenfen Zheng,Qin Xu,Jinchun Xu,Guizheng Zou,Lingling Li*and Jun-Jie Zhu*,Efficient Solid-State Electrochemiluminescence from High-QualityPerovskite Quantum Dot Films,Anal. Chem., 2017, 89, 8212-8216.(IF: 6.320)Jingjing Xue, Xinyi Chen, Shanglin Liu, Fenfen Zheng, Li He, Lingling Li*, Junjie Zhu*, Highly Enhanced Fluorescence of CdSeTe Quantum Dots Coated with Polyanilines via In-Situ Polymerization and Cell Imaging Application, ACS Appl. Mater. Interfaces, 2015, 7 (34), 19126–19133.(IF: 7.504)Fen-Fen Zheng and Jun-Jie Zhu*, Aptamer/Graphene Quantum Dots Capped Fluorescent Mesoporous Silica for Real-time Monitoring of Controlled Drug Release, 252nd American Chemical Society National Meeting & Exposition, August 2016, Pennsylvania Convention Center, Philadelphia, USA, Poster.