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个人简介 杨菲，浙江大学公共卫生学院，营养与食品卫生系，副教授。 教学与课程 本科生课程：营养与食品卫生学，临床营养学，实用营养与保健，管理你的健康研究生课程：公共卫生与法律法规 科研 承担项目：国家自然科学基金面上项目,  脂肪细胞通过Fas信号介导肥胖促进结直肠癌进展的作用及机制研究, 2018-2021国家自然科学基金青年项目, Fas信号对TLR信号介导的巨噬细胞炎症反应的调节作用及其机制研究, 2015-2017浙江省博士后基金择优资助计划一类资助，Fas信号在肿瘤进展中的作用研究，2012-2015 研究与成果 代表性论文：Xinliang Lu, Xianghui Kong, Hao Wu, Jiayue Hao, Sirui Li, Zichun Gu, Xianchang Zeng, Yingying Shen, Shibo Wang, Jiming Chen, Xuefeng Fei, Yi Sun, Xu Li, Lingling Jiang, Fei Yang*, Jianli Wang*, Zhijian Cai*. UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders. Cell Metabolism. 2023 Jun 14;S1550-4131(23)00209-7. doi: 10.1016/j.cmet.2023.05.011. (IF2022=29.0)(*co-corresponding author)Congcong Wang，Zihan Yi,Ye Jiao，Zhong Shen，Fei Yang*, Shankuan Zhu*. Gut Microbiota and Adipose Tissue Microenvironment Interactions in Obesity. Metabolites 2023, 13(7), 821; https://doi.org/10.3390/metabo13070821.(IF2022=4.1)(*co-corresponding author)Fei Yang* , Meng Duan* , Faxiang Zheng , Lei Yu , Yuan Wang , Guowei Wang , Jie Lin , Shuang Han , Da Gan , Zhuoxian Meng , Shankuan Zhu . Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx. Cancer Lett. 2021 Sep 15; S0304-3835(21)00470-5.(IF2021=9.756)Congcong Wang , Meng Duan1,2†, Jinhua Lin, Guowei Wang , He Gao, Mengsha Yan, Lin Chen, Jialing He, Wei Liu, Fei Yang*, Shankuan Zhu* .LncRNA and mRNA expression profiles in brown adipose tissue of obesity-prone and obesity-resistant mice. iScience.2022 Jul 20;25(8):104809. (IF2021=6.107) (*co-corresponding author)Fei Yang*, Yinxiang Wei*, ZhijianCai, Lei Yu, Lingling Jiang, Chengyan Zhang, Huanmiao Yan, Qingqing Wang, Xuetao Cao, Tingbo Liang and Jianli Wang. Activated cytotoxic lymphocytes promote tumor progression by increasing the ability of 3LL tumor cells to chemoattract MDSCs via Fas signaling. Cellular & Molecular Immunology. 12(1), 66-76, 2015. (IF2021=22.096)Fei Yang *, Wenhui Lin* , Eleanor Frost , Yan Min, Xiaochen Xu , Xiaoyan Wang , Wei Li , Yue Leng , Xueyin Zhao , Wei He , Ann W Hsing , Shankuan Zhu. Association between contact with a general practitioner and depressive symptoms during the COVID-19 pandemic and lockdown: a large community-based study in Hangzhou, China. BMJ Open, 2021. 11(8): p. e052383.(IF2021=3.006)Lei Yu*, Fei Yang* ,Fanghui Zhang, Danfeng Guo, Ling Li, Xian Wang, Tingbo Liang, Jianli Wang,Zhijian Cai and Hongchuan Jin. CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production. Cell Death Dis. 2018 Sep 5;9(9):905. (IF2021=9.685) (*co-first author)ZhijianCai*, Fei Yang*, Lei Yu, Zhou Y, Lingling Jiang, Qingqing Wang, Yunshan Yang, Lie Wang, Xuetao Cao, Jianli Wang. Activated T cell Exosomes promote tumor invasion via Fas signaling pathway. The Journal of Immunol.188(12), 5954-61, 2012. (IF2021=5.422) (*co-first author) ZhijianCai*, Wei Zhang*, Fei Yang*, Lie Yu, Zhou Yu, JiHuang Pan, Lie Wang, Xuetao Cao, Jianli Wang. Immunosuppressive exosomes from TGF-β1 gene-modified dendritic cells attenuate Th17-mediated inflammatory autoimmune disease by inducing regulatory T cells. Cell Research.22(3), 607-10, 2012. (IF2021=46.297) (*co-first author) Lei Yu*, Fei Yang*, Lingling Jiang, Yinghu Chen, Keyi Wang, FengXu, YinxiangWei,Xuetao Cao, Jianli Wang, ZhijianCai . Exosomes with membrane-associated TGF-β1 from gene-modified dendritic cells inhibit murine EAE independently of MHC restriction. European Journal of Immunology. 43(9), 2461-72. 2013. (IF2021=6.688)(*co-first author) YuehongShen*,FeiYang*，HuaWang，ZhijianCai，YipengXu，AnZhao，YingSu，GuZhang，ShaoxingZhu. Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice. PLoS One. 11(1),e0147173~e0147173, 2016. (IF=2.806)(*co-first author)Fei Yang*, Meng Duan，Shankuan Zhu，Adipocyte Fas signaling promotes meta-inflammation in obesity through its interaction with Bmx, ACN2019 oral presentation. Fei Yang*, Guowei Wang, Meng Duan，Shankuan Zhu,  Macrophage of adipose tissue inhibited adipocyte differentation via Fas signaling reducing Akt in obesity,TOS2019, E-poster杨菲*，杨敏, 全日制高校开设营养通识课程的必要性探析, 中国高等医学教育, 2017.10,250, 39-40,国内核心期刊 获得奖励 获得奖励：2017年度浙江省自然科学奖 一等奖2018年浙江省毒理学会科技奖（个人奖）2018年浙江省毒理学会第五届学术年会青年学者报告 三等奖