刘伟伟
时间:2024-04-23 16:00 来源: 作者: 点击:次
刘伟伟，男，中共党员，医学博士，浙江大学硕士研究生导师，浙大二院检验科。研究方向：从事前列腺癌诊断和发病机制研究，聚焦前列腺癌雄激素非依赖转化和肿瘤蛋白基因组学研究。主持国家和省部级课题两项，一作和通讯作者发表SCI论文10余篇，其中9篇IF>5，作为主要申请人申报发明专利3项。学术任职：中国中西医结合学会检验医学液态活检专家委员会（委员），中国研究型医院学会细胞外囊泡专业委员会（青年委员），浙江省医学会检验医学分会（青年委员），中国免疫学会（会员），浙江省免疫学会免疫技术专业委员会（青年委员）等；担任美国SCI杂志Oncology Letters (Editorial Board)成员；担任International Journal of Cancer, Journal of Experimental & Clinical Cancer, International Journal of Oncology等国际著名SCI期刊审稿人。学术论文：1. Liu C#, Liao Z, Duan X, Yu P, Kong P, Tao Z*, Liu W#*. The MYH9 Cytoskeletal Protein Is a Novel Corepressor of Androgen Receptors, Front Oncol, 2021,11(641496).2. Wang D#, Sang Y#, Sun T#, Kong P, Zhang L, Dai Y, Cao Y, Tao Z*, Liu W*. Emerging roles and mechanisms of microRNA‑222‑3p in human cancer (Review), Int J Oncol, 2021,58(5): 24.3. Sang Y, Kong P, Zhang S, Zhang L, Cao Y, Duan X, Sun T, Tao Z*, Liu W*. SGK1 in Human Cancer: Emerging Roles and Mechanisms, Front Oncol, 2021,10(608722).4. Zhang L#, Li Y#, Wang X, Ping Y, Wang D, Cao Y, Dai Y, Liu W*, Tao Z*. Five-gene signature associating with Gleason score serve as novel biomarkers for identifying early recurring events and contributing to early diagnosis for Prostate Adenocarcinoma, J Cancer, 2021,12(12): 3626-3647.5. Sun T, Wang D, Ping Y, Sang Y, Dai Y, Wang Y, Liu Z, Duan X, Tao Z*, Liu W*. Integrated profiling identifies SLC5A6 and MFAP2 as novel diagnostic and prognostic biomarkers in gastric cancer patients. Int J Oncol. 2020; 56: 460-9.6. Wang Y#, Liu Z#, Wang X#, Dai Y, Li X, Gao S, Yu P, Lin Q, Fan Z, Ping Y, Wang D, Lin X, Zheng Z, Liu W*, Tao Z*. Rapid and Quantitative Analysis of Exosomes by a Chemiluminescence Immunoassay Using Superparamagnetic Iron Oxide Particles, J Biomed Nanotechnol, 2019,15(8): 1792-1800.7. Liu W#, Wang X#, Wang Y, Dai Y, Xie Y, Ping Y, Yin B, Yu P, Liu Z, Duan X, Liao Z, Chen Y, Liu C, Li X, Tao Z*. SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT, J Exp Clin Cancer Res, 2018,37(1), doi: 10.1186/s13046-1.8. Liu W, Wang X, Liu Z, Wang Y, Yin B, Yu P, Duan X, Liao Z, Chen Y, Liu C, Li X, Dai Y, Tao Z*. SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway, Br J Cancer, 2017,117(8): 1139-1153.9. Liu W, Yin B, Wang X, Yu P, Duan X, Liu C, Wang B, Tao Z*. Circulating tumor cells in prostate cancer: Precision diagnosis and therapy, Oncol Lett, 2017,14(2): 1223-1232.10. Wang X#, Liu W#, Yin B, Sang Y, Liu Z, Dai Y, Duan X, Zhang G, Ding S, Tao Z*. An isothermal strand displacement amplification strategy for nucleic acids using junction forming probes and colorimetric detection, Microchimica Acta, 2017,184(6): 1603-1610.11. Zhang S#, Wang Z#, Liu W#, Lei R, Shan J, Li L, Wang X*. Distinct prognostic values of S100 mRNA expression in breast cancer, Sci Rep, 2017,7(39786).12. Yin B, Liu W, Yu P, Liu C, Chen Y, Duan X, Liao Z, Wang X, Pan X, Tao Z*. Association between human papillomavirus and prostate cancer: A meta-analysis, Oncol Lett, 2017,14(2): 1855-1865.13. Yu P, Duan X, Cheng Y, Liu C, Chen Y, Liu W, Yin B, Wang X, Tao Z*. Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase, Int J Mol Med, 2017,40(5): 1426-1434.14. Wang X, Liu W, Yin B, Yu P, Duan X, Liao Z, Liu C, Sang Y, Zhang G, Chen Y, Tao Z*. Colorimetric detection of gene transcript by target-induced three-way junction formation, Talanta, 2016,158:1-5.15. Liu W#, Xu C#, Wan H, Liu C, Wen C, Lu H, Wan F*. MicroRNA-206 overexpression promotes apoptosis, induces cell cycle arrest and inhibits the migration of human hepatocellular carcinoma HepG2 cells, Int J Mol Med, 2014,34(2): 420-428.16. Xu CM#, Liu WW#, Liu CJ, Wen C, Lu HF, Wan FS*. Mst1 overexpression inhibited the growth of human non-small cell lung cancer in vitro and in vivo, Cancer Gene Ther, 2013,20(8): 453-460.科研项目：1. 国家自然科学基金青年科学基金项目，81802571，外泌体miRNA-222-3p介导前列腺癌雄激素非依赖转化及其机制研究，2019/01-2021/12，21万元，在研，主持。2. 浙江省卫生计生委，浙江省医药卫生科技计划项目，2019RC039，SGK1调控前列腺癌细胞自噬核内关键效应分子的筛选及其作用研究，2019/01-2021/12，3万元，在研，主持。3. 国家自然科学基金青年科学基金项目，81702958，CRABP2基因与前列腺癌发生发展关系的分子机制研究、2018/01-2020/12，19万元，在研，参加。（排第4）4. 国家自然科学基金青年科学基金项目，81701373，细胞周期调控因子FOXM1的乙酰化促进MnSOD转录抑制细胞衰老的分子机制研究， 2018/01-2020/12，20万元，在研，参加。（排第7）5. 浙江省自然科学基金一般项目，LY16H160023，受体酪氨酸激酶RON介导前列腺癌雄激素非依赖性转化的机制研究，2016/01-2018/12，9万元，已结题，参加。（排第3）6. 浙江省自然科学基金一般项目，LY15H200002，EphA3激酶受体与AR受体在前列腺癌发展过程中的相互作用关系研究，2015/01-2017/12，8万元，已结题，参加。（排第4）7. 国家自然基金地区科学基金项目，81360032，牛磺酸对PUMA介导缺血再灌注心肌细胞凋亡的抑制作用，2014/01-2017/12，49万元，已结题，参加。（排第9） |