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科学研究 Scientific Research 研究方向：1、生物活性材料（骨修复、组织再生）；2、生物材料表面改性（骨修复）；3、抗菌材料（抗菌、骨修复、组织再生）；4、药物递送系统。Research Fields:1. Surfaces & Interfaces of Bioactive materials2. Surface Modification3. Bioactive materials for Antibacterial Activity3. Drug Delivery Systems主持或参加科研项目（课题）及人才计划项目情况：1.青年科学基金项目，51801158，多孔钛表面双管径TiO2纳米管层的设计及其双药控释抗菌与骨整合，主持。2.中国博士后科学基金面上项目，2018M633583，TiO2纳米管负载活性元素及肽的控释抗菌行为与骨整合，主持。3. 陕西省自然科学基础研究计划一般项目，2018JQ8018，钛酸锶纳米管负载LL37的pH响应性控释抗菌行为及骨整合机制，主持。4.中央高校基本科研业务费，3102019smxy004，3D打印多孔钛表面自组装双功能涂层及其骨整合机制，主持。5.西北工业大学基本科研启动费资助项目，3102017OQD051，多孔钛表面TiO2纳米管涂层构建及其骨整合性，主持。6. 陕西省自然科学基金面上项目, 2023-JC-YB-290, 基于GelMA的互穿双交联网络水凝胶的光热抗菌与成骨机制, 主持。Fundings1. National Natural Science Foundation of China (No.51801158).2. China Postdoctoral Science Foundation (No.2018M633584).3. Natural Science Foundation of Shaanxi Province (No.2018JQ8018).4. Fundamental Research Funds for the Central Universities (No. 3102019smxy004).5. Fundamental Research Funds for the Central Universities (No. 3102017OQD051).6. Natural Science Foundation of Shaanxi Province (No.2023-JC-YB-290).

教育教学

学术成果 Academic Achievements 研究论文(12) Yanni Zhang, Na Sun, Mengran Zhu, Quanrun Qiu, Pengju Zhao, Caiyun Zheng, Que Bai, Qingyan Zeng, Tingli Lu, The contribution of pore size and porosity of 3D printed porous titanium scaffolds to osteogenesis, Biomaterials Advances 133 (2022) 112651.(11) Fangfang Hu, Qian Gao, Jinxi Liu, Wenting Chen, Caiyun Zheng, Que Bai, Na Sun, Wenhui Zhang, Yanni Zhang*, Tingli Lu*, Smart microneedle patches for wound healing and management, Journal of Materials Chemistry. B, 2023, 11, 2830-2851.(10) Kai Han, Que Bai, Qingyan Zeng, Na Sun, Caiyun Zheng, Wendong Wu,Yanni Zhang*, Tingli Lu*, A multifunctional mussel-inspired hydrogel with antioxidant, electrical conductivity and photothermal activity loaded with mupirocin for burn healing, Materials & Design, 2022, 217: 110598.(9) Caiyun Zheng, Que Bai，Wendong Wu，Kai Han, Qingyan Zeng，Kai Dong, Yanni Zhang*, Tingli Lu*. Study on hemostatic effect and mechanism of starch-based nano-microporous particles, International journal of biological macromolecules, 2021, 179: 517-528.(8) Yanni Zhang, Kun Wang, Kai Dong, Ning Cui, Tingli Lu, Yong Han, Enhanced osteogenic differentiation of osteoblasts on CaTiO3 nanotube film, Colloids and Surfaces B: Biointerfaces, 2020, 187, 110773.(7) Yanni Zhang, Kun Wang, Yang Song, Enping Feng, Kai Dong, Yong Han, Tingli Lu, Ca substitution of Sr in Sr-doped TiO2 nanotube film on Ti surface for enhanced osteogenic activity, Applied Surface Science, 2020, 528, 147055.(6) Yanni Zhang#, Ying Chen#, Hongchao Kou, Pengfei Yang, Yanen Wang, Tingli Lu, Enhanced bone healing in porous Ti implanted rabbit combining bioactive modification and mechanical stimulation, Journal of the Mechanical Behavior of Biomedical Materials, 2018, 86: 336-344.(5)  Zhang Yanni#, Zhang Lan, Li Bo, Han Yong*, Enhancement in sustained release of antimicrobial peptide from dual-diameter structured TiO2 nanotubes for long-lasting antibacteria and cytocompatibility, ACS Applied Materials & Interface, 2017, 9: 9449-9461.(4) Zhang Yanni#, Han Yong*, Zhang Lan, Formation and bioactivity of SrTiO3 nanotubes on titanium by modified anodization and hydrothermal treatment, Journal of Materials Science & Technology, 2016, 32: 930-936.(3) Zhang Yanni#, Han Yong*, Zhang Lan, Interfacial structure of the firmly adhered TiO2 nanotube films to titanium fabricated by a modified anodization, Thin Solid Films, 2015, 583: 151-157. (2)  Zhang Yanni#, Han Yong*, Zhang Lan, Characterization of Zn-Doped TiO2 Nanotubes Anodized on Titanium Surface, Rare Metal Materials and Engineering, 2014, 4: 68-71.(1)  Zhang Lan, Guo Jiaqi, Huang Xiaoyan, Zhang Yanni, Han Yong*, The dual function of Cu-doped TiO2 coatings on titanium for application in percutaneous implants, Journal of Materials Chemistry B, 2016, 4: 3788-3800. 授权发明专利(1)  憨勇, 张妍妮, 张兰, 改善钛基表面氧化钛纳米管结合强度的氟离子沉降阳极氧化方法, 2012.09.26, 中国, 授权：CN201210152318.2(2) 张妍妮, 王坤, 卢婷利. 3D打印多孔钛表面抗菌及促成骨的可控释药体系及制备方法, 2020.01.09, 中国, 授权：ZL202010022641.2

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