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个人经历 Personal experience 工作经历 教育经历 2021.07至今        西安市生物医学材料重点实验室，办公室主任2019.12至今        西北工业大学柔性电子研究院，讲师2016.3-2017.3      哈佛医学院麻省总院生物医学工程中心，访问学者2011.8-2019.12    第四军医大学军事毒理学教研室，讲师2008.8-2011.3      第四军医大学军事毒理学教研室，助教 2008.8-2011.6      第四军医大学卫生毒理学专业，博士2005.8-2008.6      第四军医大学卫生毒理学专业，硕士2000.8-2005.6      第四军医大学预防医学专业，学士

教育教学

教育教学 Education and teaching 招生信息 硕士招生专业：生物医药

荣誉获奖

科学研究 Scientific Research 1.   陕西省自然科学基金面上项目，2022JM-130，帕金森病中硫氧还蛋白过氧化物酶的荧光修饰与功能干预，2022/01-2023/12，5万元，在研，主持2.   中央高校基本科研业务费资助项目，D5000210861，线粒体标志物检测/调控在帕金森病诊疗中的应用，2021/01-2021/12，20万元，已结题，主持3.   宁波市自然科学基金一般项目，202003N4065，线粒体质量调控在机械灌注保护DCD供肝中的作用及机制研究，2020/07-2023/06，4万元，在研，主持4.   陕西省自然科学基金面上项目，2019JM-130，ROS-CDK1-Vps34/Tom6信号轴协同调控自噬/分裂介导肝再生的机制研究，2019/01-2020/12，3万元，已结题，主持

科学研究

学术成果 Academic Achievements Hua Bai #, Congwen Fang #, Ying Shi#, Song Zhai, An Jiang, Yingna Li, Lin Wang, Qiling Liu, Gengyao Zhou, Jiahao Cao, Jia Li*, Xuekang Yang*, Xujun Qin*, Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatecto   my in mice. Cell Death & Disease, 2023, accepted.Tao Shao#, Xianning Xu#, Lan Wang, Yu Shen, Jun Zhao, Huizi Li, Duoteng Zhang, Wei Du, Hua Bai*,  Bo Peng*, Lin Li*, A novel α-ketoamide reactivity-based two-photon fluorogenic probe for visualizing peroxynitrite in Parkinson’s disease models. Journal of Innovative Optical Health Sciences, 2023, 2250039.Chenqi Xin, Naidi Yang, Yaqi Ding, Linqi Han, Zhiqiang Zhou, Xiaolu Guo, Zhijie Fang, Hua Bai*, Bo Peng, Chengwu Zhang*, Lin Li*, Mitochondrial-targeting vitamin B3 ameliorates the phenotypes of Parkinson's Disease in vitro and in vivo by restoring mitochondrial function. Advanced Therapeutics, 2022, 5, 2200094.Jintao Li#; Jie Chen#; Hua Bai#; Haiwei Wang; Shiping Hao; Yang Ding; Bo Peng*; Jing Zhang; Lin Li*; Wei Huang*; An overview of organs-on-chips based on deep learning. Research, 2022, 2022, 9869518.Bin Fang#; Beilin Zhang; Rongxiu Zhai; Limin Wang; Yang Ding; Huizi Li; Hua Bai*; Zhenhua Wang*; Bo Peng; Lin Li; Li Fu*; Two-photon fluorescence imaging of mitochondria viscosity with water-soluble pyridinum inner salts. New Journal of Chemistry, 2022, 46, 2487-2494.Hua Bai#; Bin Fang#; Xujie Wang#; Wenjing Qin; Yuhe Chen; Dongliang Zhang; Yan Li; Bo Peng; Xuekang Yang*; Li Fu*; Lin Li*; Two-photon fluorogenic probe for visualizing PGP-1 activity in inflammatory tissues and serum from patients. Chemical Communications, 2021, 57, 13186.Hua Bai#; Yaqi Ding#; Xin Li#; Deqin Kong; Chenqi Xin; Xuekang Yang; Chengwu Zhang; Ziqiang Rong; Chuanhao Yao; Shenci Lu; Lei Ji; Lin Li*; Wei Huang*; Polydatin protects SH-SY5Y in models of Parkinson’s disease by promoting ATG5-mediated but parkin-independent autophagy. Neurochemistry International, 2020, 134: 104671.Jiaying Guo#; Bin Fang#; Hua Bai#; Limin Wang; Bo Peng; Xu-Jun Qin; Li Fu; Chuanhao Yao*; Lin Li*; Wei Huang;  Dual/Multi-responsive fluorogenic probes for multiple analytes in mitochondria: from design to applications，Trends in Analytical Chemistry, 2022, 155, 116697.Yufei Xue#; Hua Bai#; Bo Peng#*; Terence Tieu; Jiamin Jiang; Shiping Hao; Panpan Li; Mark Ric hardson; Jonathan Baell; Helmut Thissen; Anna Cifuentes; Lin Li*; Nicolas Voelcker* ; Porous silicon nanocarriers with stimulus-cleavable linkers for effective cancer therapy, Advanced Healthcare Materials, 2022, 11, 2200076.Yufei Xue#; Hua Bai#; Bo Peng*; Bin Fang; Jonathan Baell; Lin Li*; Wei Huang*; Nicolas Hans Voelcker*; Stimulus-cleavable chemistry in the field of controlled drug delivery. Chemical Society Reviews, 2021, 50, 4872-4931.Xiangyu Ou#; Xue Chen#; Xianning Xu#; Lili Xie; Xiaofeng Chen; Zhongzhu Hong; Hua Bai*; Xiaowang Liu*; Qiushui Chen; Lin Li; Huanghao Yang*; Recent development in X-ray imaging technology: future and challenges. Research 2021, 2021, 9892152.Haixiao Fang#; Meirong Wu#; Wenhui Ji; Limin Wang; Ding Chen; Naidi Yang; Qiong Wu; Changmin Yu; Jie Liu; Jinhua Liu; Hua Bai*; Bo Peng; Xiao Huang; Hai-Dong Yu*; Lin Li*; Simultaneously detecting monoamine oxidase A and B in disease cell/tissue samples using paper-based devices. Applied Bio Materials, 2020, 4 (2):1395-1402.Deqin Kong; Rui Liu; Jiangzheng Liu; Qingbiao Zhou; Jiaxin Zhang; Wenli Li; Hua Bai*; Chunxu Hai*; Cubic membranes formation in synchronized human hepatocellular carcinoma cells reveals a possible role as a structural antioxidant defense system in cell cycle progression. Frontiers in Cell and Developmental Biology, 2020, 8, 617406.Deqin Kong#; Yaqi Ding#; Jiangzhen Liu; Rui Liu; Jiaxin Zhang; Qinbiao Zhou; Zi Long; Jie Peng; Lin Li; Hua Bai*; Chunxu Hai*; Chlorogenic acid prevents paraquat-induced apoptosis via Sirt1-mediated regulation of redox and mitochondrial function. Free Radical Research, 2019, 53(6): 680-693.

学术成果

综合介绍 General Introduction 研究方向：线粒体检测调控与疾病 个人相册

综合介绍