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个人简介 Personal Profile 张南刚，男，汉族，1982年10月生，四川仁寿人，博士，副教授，硕士生导师。2006年6月获武汉大学电子科学与技术专业学士学位，2012年获武汉大学微电子学与固体电子学专业博士学位。2012年9月至今任职于武汉纺织大学电子与电气工程学院，2018年4月至今兼聘于电子科技大学（成都）生命科学与技术学院&医学装备研究所特聘副教授。2019年4月至今兼任智能微纳医学检验装备及关键技术湖北省工程研究中心和湖北省功能纤维加工及检测工程技术研究中心副主任。主要从事微流控芯片技术、生物纳米材料制备及应用、体外肿瘤检测新技术、医学检测装置及其关键技术的研究。在癌症病患外周血中循环肿瘤细胞(CTCs)的捕获及检测领域取得突破性研究进展，并在国际期刊《AdvancedMaterials》（最新影响因子: 27.398）上以内封面文章发表其研究成果，多次被《Nature》等国际权威杂志综述文章引用和好评，截止目前该论文总计它引200余次。主持并完成国家自然科学基金-青年项目1项，主持湖北省教育厅重点项目1项，主持武汉纺织大学校基金2项，完成企业横向项目1项，作为主研人员参与国家自然科学基金-重大科研仪器专项1项，作为核心成员参与湖北省教育厅湖北省高等学校优秀中青年科技创新团队计划项目1项，参与企业横向项目2项。主持和参研各项项目经费累计达590余万。近年来在AdvancedMaterials， Acs Applied Materials & Interfaces， Lab on a Chip， Journal of Translational Medicine，IEEE Transactions on BiomedicalEngineering，BiomedicalMicrodevices，Microfluid andNanofluid等国际知名期刊上发表SCI论文20余篇，授权发明专利7项，实用新型专利1项，国际专利（日本）1项。 研究方向Research Directions 微流控芯片技术、新型医学检测技术及装置 2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容：在对机电结构进行分析和优化的基础上，运用控制理论进行结构参数的调整，使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容：以仿生结构为研究对象，运用连续体结构拓扑优化设计理论和方法，对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。 科研项目 科研项目（纵向）1.       “基于微流控芯片的白血病分型FISH检测新技术研究”，湖北省教育厅重点项目，项目主持（经费额：4万），2020.01.01-2021.12-31，在研。2.       “基于纳米纤维材料的循环肿瘤细胞高效捕获与释放研究”，国家自然科学基金-青年项目，项目主持（经费额：24万），项目号：51303140，2014.01.01-2016.12.30，已结题。3.       “基于微流控技术的全自动胎儿有核红细胞分析仪”，国家自然科学基金-重大科研仪器研发专项，项目参与（经费额：640万，个人承担45万），项目号：81527801，2016.01.01-2020.12.30，已结题。4.       “微流控肿瘤检测芯片”，湖北省教育厅优秀中青年创新团队项目，项目参与（经费额：20万），2013.01.01-2016.12.31，已结题。 企业项目（横向）1.        “全自动液基FISH检测系统”，企业横向，项目参与（经费额：280万），2018.07.06-2019.12.31，已结题。2.        “大通量自动染色机开发”，企业横向，项目参与（经费额：7万），2018.07.01-2018.12.31，已结题。3.        “自动血液骨髓推片机开发”，企业横向，项目参与（经费额：15万），2018.06.11-2018.12.11，已结题。4.        “微型化声表面波检测器研发（一期）”，企业横向，项目主持（经费额：3.2万），2014.11.30-2015.05.30，已结题。 研究成果 发明专利：1.        张南刚, 周琼伟, 刘侃, 方义, 一种阶梯结构的微流控芯片及其制备方法, 发明专利, 2018.9.7, 专利授权号:ZL201510976850.X2.        张南刚，周琼伟，刘侃, 刘松林, 一种三维结构的细胞捕获与释放芯片及其制备方法, 发明专利，2017.5.31，专利授权号:ZL201510920232.3 3.        李颂战, 高易凡, 刘侃, 张南刚, 刘松林, 氧化锌纳米棒阵列的微粒释放芯片、制备方法及释放方法, 发明专利， 2017.10.17，专利授权号:ZL201510920209.44.        刘侃, 汪胜祥, 张南刚, マイクロ流体細胞の捕獲チップ及びの製作方法, 国际(日本)发明专利，2017.6.23，专利授权号: 特许第6163560号5.        刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种利用微流芯片捕获肿瘤细胞的方法, 发明专利, 2015.04.15, 专利授权号: ZL201310359159.86.        刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种微流芯片的制备方法, 发明专利, 2015.01.14, 专利授权号: ZL201310310907.37.        刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种能够捕获肿瘤细胞的微流芯片, 发明专利, 2014.11.19, 专利授权号: ZL201310360654.08.        刘侃, 汪胜祥, 张南刚, 一种微流体细胞捕获芯片及其制备方法, 发明专利, 2014.06.18, 专利授权号:ZL201210442637.79.        赵兴中, 王晓明, 张南刚, 一种三维高通量药物筛选芯片及其制备方法, 实用新型专利，2012.07.04, 专利授权号:CN200810046929.2论文发表：1.      An AutomatedDetection of Influenza Virus based on 3-D Magnetophoretic Separation andMagnetica Label, Shaoli Hong†, Nangang Zhang†, Li Qin, ManTang, Zhao Ai, Aiju Chen, Kan Liu*, Analyst,2020(Accept) (二区，IF=3.978) (共同一作)2.      Simultaneous andAutomated Detection of Influenza a Virus Hemagglutinin H7 and H9 Based on Magnetismand Size Mediated Microfluidic Chip, Shuibing Wang, Zhao Ai, Zefen Zhang, ManTang, Nangang Zhang, Fen liu,Gujing Han, Shaoli Hong*, Kan Liu*, Sensors and Actuators B: Chemical, 2020,Volume 308, 127675 (一区Top，IF=7.1)3.      NegativeDepletion Mediated Brightfield Circulating Tumor Cell Identification Strategyon Microparticle-Based Microfluidic Chip, Shuibing Wang, Shaoli Hong, ShijiaCai, Jia Lei, Jinyao Chen, NangangZhang，Zhao Ai, KanLiu*, Man Tang*, Journal of Nanobiotechnology, 2020,18(1),70(二区，IF= 6.518)4.      High-performanceMultiplex Microvalves Fabrication And Using for Tumor Cells Staining On A MicrofluidicChip, Shaoli Hong, Man Tang, Zhengqi Chen, Zhao Ai, Feng Liu, Shuibing Wang, Nangang Zhang*, Kan Liu*, Biomedical Microdevices, 2019: 21,87 (三区，IF= 2.176) (通讯作者)5.      Simple and ConvenientMicrofluidic Flow Rate Measurement Based on Microbubble Image Velocimetry, ManTang, Feng Liu, Jia Lei, Zhao Ai, Shaoli Hong, Nangang Zhang*，Kan Liu*，MicrofluidNanofluid,2019,23(11),118(三区，IF= 2.489) (通讯作者)6.      HighlyEfficient Isolation of Circulating Tumor Cells Based on Multiple BiophysicalProperties Using a Simple Wedge-shaped Microfluicdic Device, Luman Qin, WeiZhou, Shoukun Zhang, Boran Cheng, Shubin Wang, Songzhan Li, Yanqin Yang,Shengxiang Wang, Kan Liu, NangangZhang*, IEEE Transactions on Biomedical Engineering, 2019(66), 1536-1541 (二区，IF= 4.424) (通讯作者)7.      Generation ofLinear and Parabolic Concentration Gradients by Using a Christmas Tree-shapeMicrofluidic Network, Qilong Shen, Qiongwei Zhou, Zhigang Lu, Nangang Zhang*, WuhanUniversity Journal of Natural Sciences, 2018, Vol.23, No.3, 244-250. (通讯作者)8.      A SimplePyramid-shaped Microchamber towards Highly Efficient Isolation of CirculatingTumor Cells from Breast Cancer Patients, Feng Liu, Shuibing Wang, Zhigang Lu,Yumei Sun, Chaogang Yang, Qiongwei Zhou, Shaoli Hong, Shengxiang Wang, BinXiong, Kan Liu, Nangang Zhang*,BiomedicalMicrodevices, 2018, 20:83. (三区，IF=2.176) (通讯作者)9.      Wedge-shaped Microfluidic Chip for Circulating Tumor Cells Isolation andIts Clinical Significance in Gastric Cancer, Chaogang Yang†, Nangang Zhang†, Shuyi Wang,Dongdong Shi, Chunxiao Zhang, Kan Liu, and Bin Xiong, Journal of Translational Medicine, 2018, 16:139. (二区，IF=4.124) (共同一作)10.  Platelet-LeukocyteHybrid Membrane-Coated Immunomagnetic Beads for Highly Efficient and HighlySpecific Isolation of Circulating Tumor Cells, Lang Rao, Qian-Fang Meng, QinqinHuang, Zixiang Wang, Guang-Tao Yu, Andrew Li, Weijie Ma, Nangang Zhang, Shi-Shang Guo, Xing-Zhong Zhao, Kan Liu*,Yufeng Yuan*, and Wei Liu*, Advanced Functional Materials, 2018,1803531. (一区Top，IF=16.836) 11.  Enhanced Performanceof Multi-dimensional CoS nanoflake/NiO Nanosheet Architecture with Synergetic Effectfor Asymmetric Supercapacitor, Yanqin Yang, Songzhan Li, Feng Liu, Jian Wen, Nangang Zhang, Shengxiang Wang,Kan Liu, Nanotechnology, 29(45),2018. (二区Top，IF=3.551)12. Highly Efficient Isolation and Releaseof Circulating Tumor Cells Based on Size-dependent Filtration and DegradableZnO Nanorods Substrate in a Wedge-shaped Microfluidic Chip, Songzhan Li, YifanGao, Xiran Chen, Luman Qin, Boran Cheng, Shubin Wang, Shengxiang Wang, GuangxinZhao, Kan Liu, Nangang Zhang*,BiomedicalMicrodevices, 2017, 19(4), 93. (三区，IF=2.176) (通讯作者)13.  PMMA MicrofluidicChip Fabrication Using Laser Ablation and Low Temperature Bonding with OCA Filmand LOCA, Kan Liu, Jianzhen Xiang, Zhao Ai, Shoukun Zhang, Yi Fang, Ting Chen,Qiongwei Zhou, Songzhan Li, Shengxiang Wang, Nangang Zhang*, MicrosystemTechnologies, 2017, 23(6), 1937-1942. (四区，IF=1.737) (通讯作者)14.  Bidirectional Electroluminescencefrom p-SnO2/i-MgZnO/n-ZnO Heterojunction Light-emitting Diodes, Yanqin Yang,Songzhan Li, Feng Liu, Nangang Zhang,Kan Liu, Shengxiang Wang, Guojia Fang, Journal of Luminescence, 2017,186, 223-228. (二区，IF=3.28)15.  Capture andRelease of Cancer Cells by Combining On-Chip Purification and Off-ChipEnzymatic Treatment，Xiaolei Yu†, Bingrui Wang†, Nangang Zhang†, Changqing Yin, Hao Chen, LinglingZhang, Bo Cai, Zhaobo He, Lang Rao, Wei Liu, Fu-Bing Wang, Shi-Shang Guo, Xing-ZhongZhao, Acs Applied Materials & Interfaces, 2015, 7(43), 24001-24007. (1区Top，IF=8.758) (共同一作)16.  Self-amplifiedPiezoelectric Nanogenerator with Enhanced Output Performance: The SynergisticEffect of Micropatterned Polymer Film and Interweaved Silver Nanowires, ChangLiu, Bo Hua, Sujian You, Chenghao Bu, Xiaolei Yu, Zhenhua Yu, Nian Chen, BoCai, Huiqin Liu, Shasha Li, Lingling Zhang, Shengxiang Wang, Kan Liu, Nangang Zhang, Wei Liu,Shi-shang Guo*, and Xing-Zhong Zhao, Applied Physics Letters, 2015, 106,163901.  (二区Top，IF=3.597)17.  Self-poweredBlue-sensitive Photodetector Based on PEDOT: PSS/SnO2 MicrowiresOrganic/inorganic p-n Heterojunction, Songzhan Li, Shengxiang Wang, Kan Liu, Nangang Zhang, Zhiyou Zhong, HaoLong, Guojia Fang, Applied Physics A, 2015, 119,1561-1566. (四区，IF=1.81)18.  An AutomaticMicrofluidic Sample Transfer and Introduction System，Kan Liu, Nan-Gang Zhang,Sheng-Xiang Wang, Yu-Liang Deng, MicrofluidNanofluid (2014) 16:101-108. (三区，IF= 2.489) 19.  Electrospun TiO2 Nanofiber-based Cell Capture Assay forDetecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients, Nangang Zhang, Yuliang Deng, Qidong Tai, Longye Hong, Qinglin Shen, Boran Cheng, BinXiong, Hsian-Rong Tseng, Shi-Shang Guo, Kan Liu, Xing-Zhong Zhao, Advanced Materials, 2012, 24, 2756-2760. (一区Top，IF=27.398) (第一作者，内封面文章)20.  Generation of Disk-like Hydrogel Beads for Cell Encapsulation and ManipulationUsing a Droplet-based Microfluidic Device, Kan Liu†, Yuliang Deng†, NangangZhang†, Sizhe Li，Huijiang Ding,Feng Guo, Wei Liu, Shi-ShangGuo, Xing-Zhong Zhao, Microfluid and Nanofluid, 2012, 13(5),761-767. (三区，IF= 2.489) (共同一作)21.  An Inverted Fabrication Method Towards A Flexible Dye Sensitized SolarCell Based on a Free-standing TiO2 Nanowires Membrane, Bolei Chen, Hao Hu,Qidong Tai, Nangang Zhang, Feng Guo, Bobby Sebo, Wei Liu, JikangYuan, Jianbo Wang, Xing-Zhong Zhao, Electrochimica Acta, 2012, 59,581-586. (二区Top，IF=6.215)22.  Rapid Purification of Cell EncapsulatedHydrogel Beads from Oil Phase to Aqueous Phase in a Microfluidic Device, YuliangDeng†,Nangang Zhang†, Libo Zhao, Xiaolei Yu, Xinghu Ji, Wei Liu,Shi-Shang Guo, Kan Liu, Xing-Zhong Zhao, Lab Chip, 2011, 11, 4117-4121. (一区Top，IF=6.774) (共同一作)23. IntegratedParallel Microfluidic Device for Simultaneous Preparation of MultiplexOptical-encoded Microbeads with Distinct Quantum Dots Barcodes, Xinghu Ji, Nangang Zhang, Wei Cheng,Feng Guo, Wei Liu, Shishang Guo, Zhike He, Xing-Zhong Zhao, Journal of Materials Chemistry, 2011, 21, 13380-13387. (一区Top，IF= 11.301)24.  Controllable Fission of Droplets and Bubbles by Pneumatic Valve, HongweiZhu, Nangang Zhang, Rongxiang He, Shize Li, ShishangGuo, Wei Liu, Xingzhong Zhao, Microfluid Nanofluid, 2011, 10, 1343-1349. (三区，IF= 2.489)25.  A Novel Method for Generation of AmphiphilicPDMS Particles by Selective Modification, Libo Zhao, Sizhe Li, Hao Hu，Zhixiao Guo, Feng Guo, Nangang Zhang, Xinghu Ji, Wei Liu, Kan Liu, Shi-Shang Guo, Xing-Zhong Zhao, Microfluid Nanofluid, 2011, 10, 453-458. (三区，IF= 2.489)26.  A MicrofluidicPlatform for Systems Pathology: Multiparameter Single-cell SignalingMeasurements of Clinical Brain Tumor Specimens, Jing Sun, Michael D.Masterman-Smith, Nicholas A. Graham, Jing Jiao, Jack Mottahedeh, Dan R. Laks,Minori Ohashi, Jason DeJesus, Ken-ichiro Kamei, Ki-Bum Lee, Hao Wang, Zeta T.F.Yu, Yi-Tsung Lu, Shuang Hou, Keyu Li, Max Liu, Nangang Zhang, Shutao Wang, Brigitte Angenieux, EduardPanosyan, Eric R. Samuels, Jun Park, Dirk Williams, Vera Konkankit, DavidNathanson, R. Michael van Dam, Michael E. Phelps, Hong Wu, Linda M. Liau, PaulS. Mischel, Jorge A. Lazareff, Harley I. Kornblum, William H. Yong, Thomas G.Graeber, Hsian-Rong Tseng, Cancer Research, 2010, 70, 6128-6138. (一区Top，IF=9.727)27.  An IntegratedMicrofluidic Device for Large-Scale In Situ Click Chemistry Screening, YanjuWang, Wei-Yu Lin, Kan Liu, Rachel J. Lin, Matthias Selke, Hartmuth C. Kolb, Nangang Zhang, Xing-Zhong Zhao,Michael E. Phelps, Clifton K. F. Shen, Kym F. Faull, Hsian-Rong Tseng, LabChip, 2009, 9, 2281-2285. (一区Top，IF=6.774) 学生信息 当前位置：教师主页 > 学生信息 入学日期 所学专业 学号 学位 招生信息 当前位置：教师主页 > 招生信息 招生学院 招生专业 研究方向 招生人数 推免人数 考试方式 招生类别 招生年份