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个人简介 孙彬，博士，副研究员，2018年11月入职浙江工业大学绿色制药协同创新中心，担任绿药机械三支部书记、浙江省药物化学与抗生素专委会秘书等职务。主要从事光催化绿色C-H官能化反应以及甾体药物合成研究，主持国家自然科学基金1项、省重点研发计划子课题1项（100万）、省自然科学基金项目1项、省教育厅项目1项、横向课题6项，共到款271万元，发表中科院1区top论文7篇，ZJUT100论文2两篇，以第一发明人授权中国发明专利5项，荣获中国石油和化学工业联合会技术发明一等奖1项，参与的专利“一种25-羟基胆固醇的合成方法”获中国专利优秀奖、中国石油和化学工业专利金奖及浙江省专利优秀奖各1项。 教学与课程 辅讲研究生课程《有机化学》 育人成果 科研项目 一、纵向课题情况1. 基于EnT二氟烷基自由基引发新策略及其在光促C(sp3)-H不对称二氟烷基化中的应用，2021.1.1-2023.12.31，国家自然科学基金委员会，30万，主持2. 基于本质安全的绿色制药技术开发及产业化应用，2020.1.1-2023.11.30，浙江省科技计划项目重点研发，100万，主持3.“PC/hv/CBrCl3”体系促进的sp2 C-H键羧基化新策略及其在喹诺酮类药物合成中的应用，2020.1.1-2022.12.31，浙江省自然科学基金项目，9万，主持4. 光-流动化学协同促进同步构建N,O稠/联杂环的新策略研究及应用，2021.1.1-2024.12.31，国家自然科学基金委员会，63万，参加5. 光促自由基串联环化反应构建稠杂环的新策略及应用，2021.1.1-2023.12.131，浙江省自然科学基金项目，10万，参加二、横向课题情况1. 维生素K3绿色合成技术开发，2021.2.1-2025.12.31，浙江花园生物高科股份有限公司，60/500，主持2. 罗库溴铵中间体缩合物合成技术开发，2018.4.1-2020.4.1，台州仙琚药业有限公司，60/65，主持3. 阿尔法骨化醇合成技术开发，2019.12.1-2024.11.30，浙江维迪生物科技有限公司20/60，主持4. 氢化可的松中间体氯代物的合成技术开发，2020.3.10-2023.3.10，台州仙琚药业有限公司，30/30，主持5. 屈螺酮中间体溴代物合成技术开发，2021.4.1-2024.3.31，台州仙琚药业有限公司20/20，主持 科研成果 1. Bin Sun, Hai-Xia Tian, Zhi-Gang Ni, Pan-Yi Huang, Hao Ding, Bing-Qian Li, Can Jin, Chun-Lei Wu, Run-Pu Shen. Photocatalyst-, metal- and additive-free regioselective radical cascade sulfonylation/cyclization of benzimidazole derivatives with sulfonyl chlorides induced by visible light. Org. Chem. Front., 2022, 9, 3669-3676.2. Xiaohui Zhuang, Lan Ling, Yingying Wang, Bingqian Li, Bin Sun, Weike Su, Can Jin. Photoinduced cascade C−N/C=O bond formation from bromodifluoroalkyl reagents, amines, and H2O via a triple-cleavage process. Org. Lett., 2022, 24, 1668-1672.3. Bin Sun, Hao Ding, Hai-Xia Tian, Pan-Yi Huang, Can Jin, Chun-Lei Wu, Run-Pu Shen. Photo-Triggered Self-Induced Homolytic Dechlorinative Sulfonylation/Cyclization of Unactivated Alkenes: Synthesis of Quinazolinones Containing a Sulfonyl Group. Adv. Synth. Catal., 2022, 364, 766-772..4. Bin Sun, Rongcheng Shi, Kesheng Zhang, Xiaoli Tang, Xiayue Shi, Jiayun Xu, Jin Yang and Can Jin. Photoinduced homolytic decarboxylative acylation/cyclization of unactivated alkenes with a-keto acid under external oxidant and photocatalyst free conditions: access to quinazolinone derivatives. Chem. Commun., 2021, 57, 6050-6053.5. Bin Sun, Xiayue Shi, Xiaohui Zhuang, Panyi Huang, Rongcheng Shi, Rui Zhu, Can Jin. Photoinduced EDA Complexes Enabled Radical Tandem Cyclization/Arylation of Unactivated Alkene with 2-Amino-1,4-naphthoquinones. Org. Lett., 2021, 23, 1862-1867. （入选高被引） 6. Bin Sun, Panyi Huang, Zhiyang Yan, Xiayue Shi, Xiaoli Tang, Jin Yang, and Can Jin, Self-Catalyzed Phototandem Perfluoroalkylation/Cyclization of Unactivated Alkenes: Synthesis of Perfluoroalkyl-Substituted Quinazolinones, Org. Lett., 2021, 23, 1026. 7. Jin Yang, Bin Sun, Hao Ding, Pan-Yi Huang, Xiao-Li Tang, Rong-Cheng Shi, Zhi-Yang Yan, Chuan-Ming Yu and Can Jin, Photo-triggered self-catalyzed fluoroalkylation/cyclization of unactivated alkenes: synthesis of quinazolinones containing the CF2R group. Green Chem., 2021, 23, 575.（入选高被引）8. Bin Sun, Rui Zhu, Xiaohui Zhuang, Xiayue Shi, Panyi Huang, Zhiyang Yan, Chuanming Yu,and Can Jin, Visible Light/Tertiary Amine Promoted Synergistic Hydroxydifluoroacetamidation of Unactivated Alkenes under Air，Org. Lett., 2021, 23, 617.9. Xiaohui Zhuang, Xiayue Shi, Rui Zhu, Bin Sun, WeiKe Su, and Can Jin, Photocatalytic Intramolecular Radical Cyclization involved Synergistic SET & HAT: Synthesis of 3,3-Difluoro-γ-Lactams, Org. Chem. Front., 2021, 8, 736.10. Jiayang Wang, Bin Sun, Liang Zhang, Tengwei Xu, Yuanyuan Xie and Can Jin, Transition-metal-free direct C-3 cyanation ofquinoxalin-2(1H)-ones with ammonium thiocyanate as the “CN” source, Org. Chem. Front., 2020, 7, 113.11. Can Jin, Zhiyang Yan, Bin Sun, and Jin Yang, Visible-Light-Induced Regioselective Alkylation of Coumarins via Decarboxylative Coupling with N‑Hydroxyphthalimide Esters, Org. Lett., 2019, 21, 2064.12. Bin Sun, Deyu Li, Xiaohui Zhuang, Rui Zhu, Aertuke Aisha, Can Jin, Visible-Light-Triggered Decarboxylative Alkylation of 8-Acylaminoquinoline with N-Hydroxyphthalimide Ester, Synlett, 2020, 31, 677.13. Bin Sun, Tengwei Xu, Liang Zhang, Rui Zhu, Jin Yang, Min Xu, Can Jin, Metal-Free Regioselective Alkylation of lmidazo[1,2-α]pyridines Metal-Free Regioselective Alkylation of lmidazo[1,2-α]pyridines Catalysis, Synlett, 2020, 31, 363.14. Jiayang Wang, Bin Sun, Liang Zhang, Tengwei Xu, Yuanyuan Xie, and Can Jin,Visible-Light-Induced Trifluoromethylation of Quinoxalin-2(1H)-Ones under Photocatalyst-Free Conditions, Asian J. Org. Chem., 2019, 8, 1942.15. Can Jin, Rui Zhu, Bin Sun, Liang Zhang,Xiaohui Zhuang, and Chuanming Yu, Visible-Light-Induced Remote C-H Difluoroalkylation of 8-Aminoquinolines via Debrominative Coupling with Functionalized Difluoromethyl Bromides, Asian J. Org. Chem., 2019, 8, 2213.16. Xiaohan Li, Bin Sun, Jin Yang, Xun Zhang, Jiayang Wang, Xiaohui Zhuang, Can Jin, Chuangming Yu, The Allylic Acetoxylation of 1,1-Disubstituted Alkenes Catalyzed by a Palladium(II)/Monothiadiazole Ligand System, Synlett, 2019, 30, 1479.17. Xiaohan Li, Bin Sun, Jiadi Zhou, Can Jin, and Chuangming Yu, Regioselective Acetoxylation of Terminal Olefins Using a Palladium(II)–Thiadiazole Catalyst, Eur. J. Org. Chem., 2019, 2635.18. Can Jin, Xiaohui Zhuang, Bin Sun, Deyu Li, and Rui Zhu, Merging Visible-Light Photoredox and Organoamine Catalysis for the C-3 Difluoroalkylation of Quinoxalin-2(1H)-Ones, Asian J. Org. Chem., 2019, 8, 1490. 19. Bin Sun, Jin Yang, Liang Zhang, Rongcheng Shi, Xun Zhang, Tengwei Xu, Xiaohui Zhuang, Rui Zhu, Chuanming Yu, and Can Jin, Photocatalytic Aerobic Double Friedel-Crafts Reaction of Glycine Derivatives with Anilines: An Efficient Synthesis of Diarylmethanes, Asian J. Org. Chem., 2019, 8, 2058.20. Zhiyang Yan, Bin Sun, Xun Zhang, Xiaohui Zhuang, Jin Yang, Weike Su, and Can Jin, Construction of C(sp2)-C(sp3) Bond between Quinoxalin-2(1H)-ones and N-Hydroxyphthalimide Esters via Photocatalytic Decarboxylative Coupling, Chem. Asian J., 2019, 14, 3344.21. Bin Sun, Yao Wang, Deyu Li, Can Jin, and Weike Su, A copper/O2-mediated direct sp3 C-H/N-H cross dehydrogen coupling reaction of acylated amines and N-aryl glycine esters, Org. Biomol. Chem., 2018,16, 2902.22. Bin Sun, Shi Yin, Xiaohui Zhuang, Can Jin and Weike Su, Selectfluor-induced C(sp2)-O coupling reaction of N-substituted anilines with hydroxylamine derivatives, Org. Biomol. Chem., 2018, 16, 6017.23. Bin Sun, Zhiyang Yang, Can Jin, Weike Su, (Diacetoxyiodo)benzene-Mediated Transition-Metal-Free Amination of C(sp3)-H Bonds Adjacent to Heteroatoms with Azoles: Synthesis of N-Alkylated Azoles, Synlett, 2018, 29, 2432.24. Bin Sun, Jiacheng Deng, Deyu Li, Can Jin, Weike Su, Photocatalytic aerobic cross-coupling reaction of N-substituted anilines with N-aryl glycine esters: Synthesis of α-aryl α-amino esters, Tetrahedron Lett., 2018, 59, 4364. 社会服务 担任浙江省药学会药物化学与抗生素专委会秘书兼青委会委员