柳鹏福
时间:2024-04-27 21:06 来源: 作者: 点击:次
个人简介 教育经历2003/08-2009/6 华中农业大学 微生物学 硕博士Ø 研究方向:蛋白质定向进化方法和细菌群体感应系统的研究 刘子铎教授 Ø 毕业论文:一种新的富含GC基因随机诱变方法的建立和细菌群体感应系统的研究 1998/09-2002/06 河南大学 发酵工程 学士 工作经历2016/05-至今 浙江工业大学绿色制药协同创新中心 助理研究员Ø 研究方向:酶工程和合成生物学 2011/12-2016/04 中科院上海高等研究院 助理研究员Ø 研究方向:工业生物技术 2009/11-2011/11 中科院上海生命科学研究院 博士后Ø 研究方向:工业生物技术Ø 合作导师 杨晟研究员 教学与课程 负责《认识实习》和《生产实习》的本科教学工作 育人成果 科研项目 承担课题情况: 国家青年自然科学基金:海洋环境中群体淬灭酶资源的发掘及其酶学性质和催化机制的研究 项目批准号:41306142 经费来源:国家基金委 项目起止时间:2014-2016 参与项目情况:1. 国家重点研发计划课题:海洋微生物先导物的规模化制备及关键技术研究 项目编号:2018YFC0311004 经费来源:科技部 项目起止时间:2018.08-2021.12 2. 国家重点研发计划“合成生物学”专项课题,高值化合物的高产优产机制及产业化实施 项目编号:2018YFA0900404 经费来源:科技部 项目起止时间:2019.07-2024.06 3. 中国与塞尔维亚政府间科技合作项目:生物法生产大宗化学品; 项目编号:(1-3);经费来源:科技部;项目起止时间:2011.5-2013.6: 科研成果 已发表论文:(1)Zhenyu Zhang, Pengfu Liu(并列第一作者), Weike Su, Huawei Zhang, Wenqian Xu, and Xiaohe Chu, Metabolic engineering strategy for synthetizing trans-4-hydroxy-l-proline in microorganisms,Microbial Cell Factories, 2021,20(1)87(2)Pengfu Liu, Yan Chen, Zongze Shao, Jianwei Chen, Jiequn Wu, Qian Guo, Jiping Shi, Hong Wang*, Xiaohe Chu*. AhlX, an N-acylhomoserine Lactonase with Unique Properties. Marine Drugs, 2019, 17(7),387(3)Yuchi Lu, Yan Chen, Qinglin Wang, Xinrui Hao, Pengfu Liu*, Xiaohe Chu*. Organic-Inorganic Hybrid Nanocomposites: A Novel Way to Immobilize l-Glutamate Oxidase with Manganese Phosphate. Journal of Inorganic and Organometallic Polymers and Materials, 2019,10(4)Dong Wei, Jun song Sun, Jiping Shi, Pengfu Liu*, Jian Hao*, New strategy to improve efficiency for gene replacement in Klebsiella pneumonia, Journal of Industrial Microbiology and Biotechnology, Journal of Industrial Microbiology & Biotechnology , 2013, 40(5) :523-527.(5)Pengfu Liu, Yang Gao, Wei Huang, Zongze Shao, Jiping Shi, Ziduo Liu*. A novel bioassay for high-throughput screening microorganisms with N-acyl homoserine lactone degrading activity. Applied Biochemistry and Biotechnology. 2012, 167: 73-80.(6)Pengfu Liu, Yuzhi Hong, Yongjun Lin, Xiaoyu Fu, Ling Lin, Congcong Li, Xin Meng, Ziduo Liu*. A frequency-controlled random mutagenesis method for GC-rich genes. Analytical Biochemistry. 2009, 388: 356–358.(7)Wang Dexin, Zhou Jidong, Chen Chuan, Wei Dong, Shi Jiping, Jiang Biao, Liu Pengfu, Hao Jian*. R-acetoin accumulation and dissimilation in Klebsiella pneumoniae. Journal of Industrial Microbiology & Biotechnology, 2015. 42(8), 1105-1115(8)Chen, Chuan; Wei, Dong; Liu, Pengfu; Wang, Min; Shi, Jiping*; Jiang, Biao; Hao, Jian*. Inhibition of RecBCD in Klebsiella pneumoniae by Gam and its effect on the efficiency of gene replacement. J. Basic Microbiol. 2015, 55, 1–7(9)Wei Huang, Yongjun Lin, Shuyuan Yi, Pengfu Liu, Jie Shen, Zongze Shao, Ziduo Liu. QsdH, a Novel AHL Lactonase in the RND-Type Inner Membrane of Marine Pseudoalteromonas byunsanensis Strain 1A01261. PLoS One, 7(10):e46587, 2012.IF:3.73(10)Xiaoyu Fu, Pengfu Liu, Ling Lin, Yuzhi Hong, Xiaoluo Huang, Xin Meng, Ziduo Liu. A Novel Endoglucanase (Cel9P) From a Marine Bacterium Paenibacillus sp. BME-14. Appl Biochem Biotechnol, Mar;160(6):1627-36, 2010.(11)Xiaoyu Fu, Xiaoluo Huang, Pengfu Liu, Ling Lin, Gaobing Wu, Chanjuan Li, Chunfang Feng, Yuzhi Hong, Cloning and Characterization of a novel Mannanase from Paenibacillus sp. BME-14. J Microbiol Biotechnol, Mar;20(3):518-24, 2010.(12)Ling Lin, Xin Meng, Pengfu Liu, Yuzhi Hong, Gaobing Wu, Xiaoluo Huang, Congcong Li, Junli Dong, Liang Xiao,Ziduo Liu. Improved Catalytic Efficiency of Endo-β-1, 4-glucanase from Bacillus subtilis BME-15 by Directed Evolution. Appl Microbiol Biotechnol. 2009 Mar; 82 (4): 671-9.(13)Chanjuan Li, Yuzhi Hong, Zongze Shao, Ling Lin, Xiaoluo Huang, Pengfu Liu, Gaobing Wu, Xin Meng, Ziduo Liu. A novel alkali-stable, cellulase-free xylanase from deep-sea Kocuria sp. Mn22. J. Microbiol. Biotechnol, 2009 Sep;19(9):873-80.已授权发明专利(1)柳鹏福,史吉平,郝健,薛鹏飞,姜标,一种N-酰基高丝氨酸内酯酶及其编码基因和重组菌,20190430,中国,ZL201610105269.5(2)柳鹏福,孙立洁,王纪,袁丽霞,刘洋,吴金勇,陈祥松,史吉平,姚建铭,一种产 N-乙酰神经氨酸大肠杆菌工程菌及其构建方法和应用,20150318,中国, ZL 201310600843.0(3)郝健,魏东,柳鹏福,孙月红,史吉平,姜标,利用克雷伯氏肺炎杆菌两段发酵生产 2-酮基-D-葡萄糖酸的方法,中国,ZL201310012784.5。(4)郝健,魏东,柳鹏福,史吉平,姜标,利用短同源序列进行克雷伯氏肺炎杆菌基因重组的方法,中国,ZL201210388546.X。(4)史吉平,刘莉,孙俊松,林增祥,柳鹏福,姜标. 利用小麦麸皮发酵生产丙酮-丁醇-乙醇的方法,中国,ZL201210139927.4。 社会服务 |