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生命科学与技术学院   导师代码： 10483 导师姓名： 陈华富 性    别： 男 特    称： ****，国家杰青获得者 职    称： 教授 学    位： 工学博士学位 属    性： 专职 电子邮件： chenhf@uestc.edu.cn 学术经历：   1） 2012 年- 电子科技大学 磁共振脑成像中心 主任 2） 2009 年- 电子科技大学 神经信息教育部重点实验室 副主任 3） 2005/06-至今,电子科技大学生命科学与技术学院,教授,博士导师。电子科技大学医学影像中心主任。主要从事磁共振成像数据处理方法和应用研究,神经网络,脑功能成像和优化算法以及博士生,研究生和本科生的教学工作。 4） 2005/09-2006/03,在美国德克萨斯大学脑功能研究中心作访问学者（合作者高家红教授）。主要从事磁共振成像数据处理方法研究。 5） 2005/07-2007/06,中国科学院生物物理研究所/研究生院脑与认知国家重点实验室,博士后。博士后论文题目：《功能磁共振成像分析方法和应用研究》,合作导师：陈霖院士。 6） 2002/01-2005/05,电子科技大学生命科学与技术学院,副教授,主要从事磁共振成像数据处理算法研究,及神经网络和优化算法本科生的教学工作。 个人简介：   陈华富，男，电子科技大学，****特聘教授，国家杰出青年基金获得者。2020年爱思唯尔中国高被引学者，2020年中国区神经科学领域全球2%顶尖科学家。四川天府****计划“天府创新领军人才”，四川省教书育人名师，中国图像图形学会理事、组织建设委员会和视觉认知与计算专业委员会副主任委员，电子科技大学神经信息教育部重点实验室副主任, 高场磁共振成像四川省重点实验室执行副主任。主要从事磁共振脑影像数据模式识别的人工智能与机器学习方法研究、神经与精神疾病影像机制研究，探测疾病的典型影像学特征，为临床诊断和评估提供影像学依据。主持了4项国家自然基金重点和3项科技部项目等20余项科研项目。作为通信作者在Science Advance ，Nature Communications， Molecular Psychiatry，Brain, PLOS Biology, Neurology, Schizophrenia Bulletin, Cerebral Cortex等杂志发表SCI论文300余篇，被SCI引用8400次，入选ESI高倍引论文11篇、热点论文2篇，获四川省科技进步自然科学类一等奖。 科研项目：   1) 国家自然科学基金重点项目（62036003）,基于机器学习的帕金森大脑运动感知网络关键技术与方法, 290万，2021/1-2025/12, 负责人 2) 科技部重点研发2030（2018AAA0100705），脑网络因果模型与抑郁症研究，175万，2019/1-2022/12, 负责人 3) 国家自然科学基金联合重点项目（U1808204）, 多中心、多模态 抑郁症脑影像信息模式识别方法与关键技术,250万， 2019/1-2022/12, 负责人 4) 国家自然科学基金重点项目（61533006）, 抑郁症视听通道情绪加工脑机制的多模态脑网络计算模型，280万，2016/1-2020/12, 负责人 5) 863计划（2015AA020505），癫痫脑神经多模态定量化关键技术，351万， 2015/1-2017/12, 负责人 6） 国家杰出青年基金（61125304），脑功能模式识别方法及应用研究,240万,2012/01-2015/12，负责人（个人） 7） 国家自然基金重点项目（61035006）,多模态脑功能信息融合理论和方法,220万,2011/01-2014/12,负责人。 研究成果：   部分代表性论文： 2021年 1) Jiao Li; Jakob Seidlitz; John Suckling; Feiyang Fan; Gong-Jun Ji; Yao Meng; Siqi Yang; Kai Wang; Jiang Qiu; Huafu Chen*; Wei Liao*; ？Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures, Nature Communications, 2021, 12:1647. 2) Jinqiang Zhang ， Peijing Rong ，Lijuan Zhang ，Hui He ，Tao Zhou，Yonghua Fan， Li Mo , Qiuying Zhao, Yue Han ，Shaoyuan Li ，Yifei Wang ，Wan Yan，Huafu Chen *，Zili You*，IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis. Science Advance，2021，7（12）： eabb9888 3) Siqi Yang, Konrad Wagstyl, Yao Meng, Xiaopeng Zhao, Jiao Li, Peng Zhong, Bing Li, Yun Shuang Fan, Huafu Chen*, Wei Liao*, Cortical patterning of morphometric similarity gradient reveals diverged hierarchical organization in sensory-motor cortices, Cell Reports, 2021, 36(8): 109582 4) Jinming Xiao, Huafu Chen*, Xiaolong Shan, Changchun He, Ya Li, Xiaonan Guo, Heng Chen, Wei Liao, Lucina Q. Uddin*, Xujun Duan*. Linked social–communication dimensions and connectivity in functional brain networks in autism spectrum disorder. Cerebral Cortex,2021 ， 31（8）:3899-3910 5) Xiaonan Guo, Xujun Duan*, John Suckling, Jia Wang, Xiaodong Kang, Heng Chen, Bharat B. Biswal, Jing Cao, Changchun He, Jinming Xiao, Xinyue Huang, Runshi Wang, Shaoqiang Han, Yun-Shuang Fan, Jing Guo, Jingping Zhao, Lijie Wu*, Huafu Chen*, Mapping progressive gray matter alterations in early childhood autistic brain, Cerebral Cortex, 2020, DOI: 10.1093/cercor/bhaa304. 6) Rong Li, Jiale Yang, Liyuan Li, Fei Shen, Ting Zou, Hongyu Wang, Xuyang Wang1, Jiyi Li, Chijun Deng, Xinju Huang, Chong Wang,Zongling He, Fengmei Lu, Ling Zeng and Huafu Chen*, Integrating Multilevel Functional Characteristics Reveals Aberrant Neural Patterns during Audiovisual Emotional Processing in Depression, Cerebral Cortex, 2021, DOI: 10.1093/cercor/bhab185 7) Heng Chen#, Fengmei Lu#, Xiaonan Guo, Yajing Pang, Changchun He, Shaoqiang Han, Xujun Duan*, Huafu Chen*, Dimensional analysis of atypical functional connectivity of major depression disorder and bipolar disorder, Cerebral Cortex, 2021, DOI: 10.1093/cercor/bhab296 8) Xujun Duan#, Changchun He#, Jianjun Ou, Runshi Wang, Jinming Xiao, Lei Li, Renrong Wu, Yan Zhang*, Jingping Zhao*, Huafu Chen*, Reduced hippocampal volume and its relationship with verbal memory and negative symptoms in treatment-naive first-episode adolescent-onset schizophrenia, Schizophrenia Bulletin, 2021：47（1） ：64–74 9) Meng Yao, Yang Siqi, Chen Huafu*,Li Jia, Xu qiang; zhang Qirui, Lu Guangming, Zhang Zhiqiang*, Liao Wei*.Systematically disrupted functional gradient of the cortical connectome in generalized epilepsy: Initial discovery and independent sample replication,Neuroimage,230, DOI 10.1016/j.neuroimage.2021.117831 10) Qing Gao？ , Yu Xianga , Jiabao Zhanga , Ning Luoa , Minfeng Lianga , Lisha Gonga , Jiali Yua , Qian Cui c , Jorge Sepulcre d,e , Huafu Chen*，A reachable probability approach for the analysis of spatio-temporal dynamics in the human functional network，NeuroImage，243,118497 11) Wei Huanga , Hongmei Yan* , Kaiwen Cheng , Chong Wang , Jiyi Li , Yuting Wang , Chen Li , Chaorong Li , Yunhan Li , Zhentao Zuo* , Huafu Chen*, A neural decoding algorithm that generates language from visual activity evoked by natural images，Neural Networks，2021，144:90-100 12) Yushuang Fan, Liang Li, Yue Peng, Haoru Li, Jing Guo, Meiling Li, Siqi Yang, Meng Yao, Jingping Zhao, Hesheng Liu, Wei Liao, Xiaonan Guo, Shaoqiang Han, Qian Cui, Xujun Duan, Yong Xu*, Yan Zhang*, Huafu Chen*, Individualspecific functional connectome biomarkers predict schizophrenia positive symptoms during adolescent brain maturation, Human Brain Mapping,2021，42（5）: 1475 -1484 13) Rong Li, Hongyu Wang, Liangcheng Wang, Leiyao Zhang, Ting Zou, Xuyang Wang, Wei Liao, Zhiqiang Zhang*, Guangming Lu*, Huafu Chen*. Shared and distinct global signal topography disturbances in subcortical and cortical networks in human epilepsy. Human Brain Mapping, 2020, doi: 10.1002/hbm.25231 14) Huang Wei，Yan Hongmei*，Cheng Kaiwen，Wang Yuting，Wang Chong ，Li Jiyi，Li Chen，Li Chaorong，Zuo Zhentao*， Chen Huafu*，A dual-channel language decoding from brain activity with progressive transfer training，HUMAN BRAIN MAPPING，2021，DOI 10.1002/hbm.25603 15) He Changchun, Cortes Jesus M, Kang Xiaodong, Cao Jing, Chen Heng , Guo Xiaonan, Wang Ruishi, Kong Lingyin, Huang Xinyue, Xiao Jinming, Shan Xiaolong, Feng Rui, Chen, Huafu, Duan, Xujun. Individual--based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorde，HUMAN BRAIN MAPPING，2021,42（10）：3282-3294 2020年 16) Xiangyang Zhang#*, Mi Yang#, Xiangdong Du, Wei Liao, Dachun Chen, Fengmei Fan, Meihong Xiu, Qiufang Jia, Yuping Ning, Xingbing Huang, Fengchun Wu, Jair C. Soares, Bo Cao, Li Wang, Huafu Chen*. Glucose disturbances, cognitive deficits and white matter abnormalities in first-episode drug-na？ve schizophrenia. Molecular Psychiatry, 2020,25:3220-3230 17) Jing Guo#, Hui Chen#, Bharat B. Biswal, Xiaonan Guo, Huangbin Zhang, Limeng Dai, Yuhan Zhang, Liang Li, Yun-Shuang Fan, Shaoqiang Han, Juan Liu, Liu Feng, Qiannan Wang, Jian Wang*, Chen Liu*, Huafu Chen*, Grey matter atrophy patterns within the cerebellum-neostriatum-cortical network in SCA3, Neurology, 2020, 95（22）：E3036-E3044 18) Danhong Wang#, Meiling Li#, Meiyun Wang, Franziska Schoeppe, Jianxun Ren, Huafu Chen, Dost Ongur, Justin Baker*, Hesheng Liu*. Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness. Molecular Psychiatry, 2020，25(9):2119-2129 19) Xujun Duan#, Maolin Hu#, Xinyue Huang, Chan Su, Xiaofen Zong, Xia Dong, Changchun He, Jinming Xiao, Haoru Li, Jinsong Tang*, Xiaogang Chen*, Huafu Chen*, Effect of risperidone monotherapy on dynamic functional connectivity of insular subdivisions in treatment-naive, first-episode schizophrenia, Schizophrenia Bulletin, 2020, 46(3): 650-660. 20) Changchun He, Huafu Chen*, Lucina Q. Uddin, Asier Erramuzpe, Paolo Bonifazi, Xiaonan Guo, Jinming Xiao, Heng Chen, Xinyue Huang, Lei Li, Wei Sheng, Wei Liao, Jesus M. Cortes*, Xujun Duan*, Structure-Function connectomics reveals aberrant developmental trajectory occurring at preadolescence in the autistic brain, Cerebral Cortex, 2020, 30(9): 5028-5037. 21) Yuyan Chen, Qian Cui*, Yun-Shuang Fan, Xiaonan Guo, Qin Tang, Wei Sheng, Ting Lei, Di Li, Fengmei Lu, Zongling He, Yang Yang, Shan Hu, Jiaxin Deng, Huafu Chen*, Progressive brain structural alterations assessed via causal analysis in patients with generalize anxiety disorder, Neuropsychopharmacology, 2020, 45 (10): 1689-1697. 22) Yao Meng; Siqi Yang; Huafu Chen*; Jiao Li; Qiang Xu; Qirui Zhang; Guangming Lu; Zhiqiang Zhang*; Wei Liao*. Systematically disrupted functional gradient of the cortical connectome in generalized epilepsy: Initial discovery and independent sample replication, Neuroimage, 2021, 230:117831; 23) Siqi Yang; Yao Meng; Jiao Li; Bing Li; Yun-Shuang Fan; Huafu Chen*; Wei Liao*. The thalamic functional gradient and its relationship to structural basis and cognitive relevance, NeuroImage, 2020, 218: 116960； 24) Wei Huang, Hongmei Yan*, Chong Wang, Jiyi Li, Xiaoqing Yang, Liang Li, Zhentao Zuo*, Jiang Zhang, Huafu Chen*, Long short-term memory-based neural decoding of object categories evoked by natural images, Human Brain Mapping, 2020, 41(15): 4442-4453. 25) Shaoqiang Han, Qian Cui*, Xiao Wang, Liang Li, Di Li, Zongling He, Xiaonan Guo, Yun-Shuang Fan, Jing Guo, Wei Sheng, Fengmei Lu, Huafu Chen*, Resting state functional network switching rate is differently altered in bipolar disorder and major depressive disorder, Human Brain Mapping, 2020, 41(12): 3295-3304. 26) Qian Cui, Wei Sheng, Yuyan Chen, Yajing Pang, Fengmei Lu, Qin Tang, Shaoqiang Han, Qian Shen, Yifeng Wang, Ailing Xie, Jing Huang, Di Li, Ting Lei, Zongling He, Huafu Chen*, Dynamic changes of amplitude of low frequency fluctuations in patients with generalized anxiety disorder, Human Brain Mapping, 2020, 41(6): 1667-1676. 27) Yun-Shuang Fan, Zehan Li, Xujun Duan, Jinming Xiao, Xiaonan Guo, Shaoqiang Han, Jing Guo, Siqi Yang, Jiao Li, Qian Cui, Wei Liao*, Huafu Chen*, Impaired interactions among white-matter functional networks in antipsychotic-naive first-episode schizophrenia, Human Brain Mapping, 2020,41(1): 230-240 28) Xiaonan Guo, Xujun Duan*, Heng Chen, Changchun He, Jinming Xiao, Shaoqiang Han, Yun-Shuang Fan, Jing Guo, Huafu Chen*, Altered inter- and intrahemispheric functional connectivity dynamics in autistic children, Human Brain Mapping, 2020, 41(2): 419-428. 2019年 29) Wei Liao, Jiao Li, Gong-Jun Ji, Guo-Rong Wu, Zhiliang Long, Qiang Xu, Xujun Duan, Qian Cui, Bharat B. Biswal, Huafu Chen*. Endless fluctuations: temporal dynamics of the amplitude of low frequency fluctuations. IEEE Transactions on Medical Imaging, 2019, 38(11): 2523-2532. 30) Meiling Li #, Danhong Wang#, Jianxun Ren, Georg Langs, Sophia Stoecklein, Brian P. Brennan, Jie Lu*, Huafu Chen*, Hesheng Liu*. Performing group-level functional image analyses based on homologous functional regions mapped in individuals. PLOS Biology, 2019, 17(3): e2007032. 31) Xiaofen Zong, Molin Hu, Spiro.P Pantazatos. J.John Mann, Gaohua Wang, Yahui Liao, Zhong-Chun Liu, Wei Liao, Tao Yao, Zongchang Li, Ying He, Luxia Lv, Deen Sang, Jiansong Tang（等同贡献）, Huafu Chen（等同贡献）, Junjie Zheng（等同贡献）, Xiaogang（等同贡献）*, A dissociation in effects of risperidone monotherapy on functional and anatomical connectivity within the default mode network. Schizophrenia Bulletin, 2019, 45(6): 1309-1318. 32) Wei Liao, Yun-Shuang Fan, Siqi Yang, Jiao Li, Xujun Duan, Qian Cui, Huafu Chen*. Preservation effect: Cigarette smoking acts on the dynamic of influences among unifying neuropsychiatric triple networks in schizophrenia. Schizophrenia Bulletin, 2019, 45(6): 1242-1250） 33) Meiling Li#, Benjamin Becker#, Junjie Zheng#, Yan Zhang, Heng Chen, Wei Liao, Xujun Duan, Hesheng Liu, Jingping Zhao, Huafu Chen*. Dysregulated maturation of the functional connectome in antipsychotic-na？ve, first episode patients with adolescent-onset schizophrenia, Schizophrenia Bulletin, 2019, 45(3): 689-697. 专业研究方向： 专业名称 研究方向 招生类别 083100生物医学工程 01生物医学工程，04医学成像与医学图像/信号处理 博士学术学位 085400电子信息 01生物医学工程 博士专业学位 083100生物医学工程 02医学成像与图像处理技术，08电子科技大学-加拿大麦吉尔大学生物医学工程-神经科学双硕士教育项目 硕士学术学位