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导航 个人简介 学习经历 工作经历 研究方向 主要论文 主要著作 承担课题,个人信息 姓名： 焦睿 部门： 理工学院 直属机构： 食品科学与工程系 性别： 女 职称： 副研究员 学位： 博士 毕业院校： 香港中文大学 电子邮箱： tjiaorui@jnu.edu.cn 办公地址： 广州市天河区黄埔大道西601第二理工楼528 通讯地址： 广州市天河区黄埔大道西601 联系方式 个人简介 焦睿老师自2006年以来一直从事功能食品及营养素对身体健康的干预研究，重点关注黄酮、类黄酮、植物多酚、植物甾醇、姜酚等功能性成分对调节脂质代谢及保护心血管健康方向的研究。相关研究成果发表SCI及EI收录论文40余篇（其中JCR 1区文章20余篇），SCI共被引频次700余次，h-index 14，其中以第一或通讯作者发表相关SCI文章10多篇，并参与撰写英文著作2篇。 学习经历 焦睿老师本科毕业于四川大学生物工程系，毕业后赴香港中文大学硕博连读，博士专业为生物化学。 工作经历 2013/12-至今，暨南大学，理工学院食品科学及工程系，副研究员2012/2-2013/11，深圳先进技术研究院，医药所，助理研究员2010/11-2012/1，深圳华大基因研究院，代谢疾病组，项目总监 主要论文 1.Sun J, Li M, Zou F, Bai S, Jiang X, Tian L, Ou S, Jiao R*(通讯作者), Bai W.Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells.Food Chem Toxicol. 2018 Mar 21. pii: S0278-6915(18)30176-5. 2.Li X, Guo J, Liang N, Jiang X, Song Y, Ou S, Hu Y, Jiao R*(通讯作者), Bai W. 6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells.Front Pharmacol. 2018 Feb 27;9:159.3.Wang Z, Pan L, Liu G, Zhang H, Zhang J, Jiang J, Xiao Y, Bai W, Jiao R*(通讯作者), Huang W. Dietary exposure to cadmium of Shenzhen adult residents from a total diet study.Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Apr;35(4):706-7144.Sun J,Xu W,Zhu C,Hu Y,Jiang X,Ou S,Su Z,Huang Y, Jiao R*（共同通讯作者）,Bai W*. Cyanidin-3-O-Glucoside Protects against 1,3-Dichloro-2-Propanol-Induced Reduction of Progesterone by Up-regulation of Steroidogenic Enzymes and cAMP Level in Leydig Cells.Front Pharmacol.2016 Nov 4; 7:399.5.Pan L, Wang Z, Peng Z, Liu G, Zhang H, Zhang J, Jiang J, Pathiraja N, Xiao Y,Jiao R* (共同通讯作者), Huang W*. Dietary exposure to lead of adults in Shenzhen city, China.Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2016 Jul; 33(7):1200-6. 6.Jiao R（第一作者）, Liu Y, Gao H, Xiao J, So KF. The Anti-Oxidant and Antitumor Properties of Plant Polysaccharides.Am J Chin Med. 2016; 44(3):463-88.7.Hou X,Jiao R（共同第一作者）, Guo X, Wang T, Chen P, Wang D, Chen Y, He CY, Chen ZY. Construction of minicircle DNA vectors capable of correcting familial hypercholesterolemia phenotype in a LDLR-deficient mouse model.Gene Ther. 2016 Aug; 23(8-9):657-63. 8.Jiao R（第一作者）, Chen JN, Peng C, Liang YT, Ma KY, Wang XB, Li YW, Lei L, Huang Y, Chen ZY. Cholesteryl Ester (CE) Species Differently Elevate Plasma Cholesterol. Journal of Agricultural and Food Chemistry. 2013, 61(46):11041-7.9.Jiao R (第一作者), Zhang Z, Yu H, Huang Y, Chen ZY. Hypocholesterolemic activity of grape seed proanthocyanidin is mediated by enhancement of bile acid excretion and up-regulation of CYP7A1. The Journal of Nutritional Biochemistry. 2010, 21(11):1134-9. 10.Jiao R (第一作者), Guan L, Yang N, Peng C, Liang Y, Ma KY, Huang Y, Chen ZY. Frequent Cholesterol Intake Up-regulates Intestinal NPC1L1, ACAT2, and MTP. Journal of Agricultural and Food Chemistry. 2010, 58:5851-7. 11.Jiao R (第一作者), Yu FF, Huang Y and Chen ZY. beta-Sitosterol Decreases but its Intake Frequency Has no Effect on Plasma Cholesterol Level. Current Topics Nutraceutical Research. 2010, 8(4):127-135.12.Chen ZY, Jiao R, Ma KY. Cholesterol-lowering nutraceuticals and functional foods. Journal of Agricultural and Food Chemistry. 2008, 56:8761-73. 13.Jiao R (第一作者), Wong YM, Yeung SY, Chen ZY. Effect of cholesterol intake frequency on serum cholesterol and lipoprotein profiles in hamsters. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2009, 238:105 14.Chen ZY, Peng C, Jiao R, Yang N. Oxidized cholesterol is more hypercholesterolemic and atherogenic than nonoxidized cholesterol in hamsters. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2009, 238:8815.鲁昊浩, 焦睿* (通讯作者),黄雪松,晏日安.6-姜酚与6-姜酚肟抗氧化性质的比较研究现代食品科技,2015,31,106-11116.郭静婷，焦睿* (通讯作者)，蒋鑫炜，李夏，李旭升，冉国敬，白卫滨. 食品功能成分对氧化三甲胺介导的动脉粥样硬化的影响. 食品科学，2018，网络见刊，CN 11-2206/TS 主要著作 1.Jiao R *（第一作者及通讯作者）, Chen JN, Huang Y, Chen ZY. CHAPTER 50: Teas (Green, Oolong, and Black). Handbook of Functional Beverages and Human Health, CRC Press Taylor & Francis Group, LLC, 2016, pp 629-639, New York.2.Wang XB，Lei L，Liu YW，Ma KY，Chen JN，Jiao R，Huang Y，Chen ZY，CHAPTER 31: Interaction of dietary calcium with genes of transporters, receptors and enzymes involved in cholesterol metabolism，Food and Nutritional Components in Focus, Preedy V.R., Royal Society of Chemistry, pp 519-529, England, 2016. 讲授课程