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颜辉 教授 生物技术学院 蚕业研究所 个人邮箱： yan_hui@just.edu.cn 办公地点： 生技楼 225# 通讯地址： 江苏省镇江市丹徒区长晖路666号 邮政编码： 212100 传真： 您是第2483 位访问者 个人简介 颜辉，男，博士，教授，硕士生导师。江苏大学博士研究生毕业，美国麻省大学进修、德国杜伊斯堡-埃森大学博士后研究。主要从事生物分析基础与应用研究。利用近红外（NIR）、荧光光谱和局部表面等离子共振（LSPR）技术，开展农产（食）品、中药材品质等方法及装备研发，以及肿瘤标志物的生物传感诊断方法研发。主持和主要参与国家自然科学基金、十四五”国家蚕桑产业技术体系项目（2016-2017、2021-2025）、江苏省重点研发计划、江苏省自然科学基金项目等10余项，主持企业委托项目5项。发表科研论文40余篇；成功转让发明专利4项；获软件著作权6件。获省部级科技进步一等奖（1/12）、三等奖（1/6）各1项。指导研究生获得明石杯”微纳传感技术与智能应用”等国赛“三等奖”2次，研究生/本科生获得“东方紫”生命科学大赛特等奖2次。研究生获得江苏科技大学优秀硕士论文2次，国家奖学金2次。2022年获指导本科生获得省团队优秀毕业论文。 研究方向 1.生物传感       生命科学（肿瘤等疾病）和食品安全等方向的检测新方法，技术手段：LSPR、荧光和SERS       将光纤与表面等离子共振（LSPR）相结合，研发检测肿瘤标志物或食品中生物质毒素等有害物质（重金属、抗生素等）的传感器及方法，用于肿瘤的早期诊断或食品安全预防，具有设备便宜、运行成本低、使用便捷等优点。2.无损检测      食品、药材质量的现场、快速检测方法及装备研发，技术手段：NIR      随着科技的进步，越来越多的手持式近红外光谱仪（MEMS技术）进入市场，这为食品、药材质量的现场、快速检测提供了基础。本团队系统的开展了近红外光谱快速无损检测应用、检测应用软件开发、近红外检测硬件装置升级改造及创制等关键技术研究，在食品、药材质量的现场质量评价、在线实时控制、工业化分拣等方面进行了系统的探索和实践，取得了一系列成果。招生方向硕士：生物学，畜牧学，畜牧，生物与医药，农业，食品加工与安全 教育经历 2016/11 - 2017/11，德国University of Duisburg-Essen进修2011/08 - 2012/02，美国University of Massachusetts Amherst进修2007/09 - 2010/12，江苏大学，博士 课程教学                     1. 药理学                    2. 免疫学 科研项目 论文著作 Selected publications  [1].Lei H, Zhu S, Liu C, Zhang W, Chen C, Yan H. Constructing the Au Nanoparticle Multimer on Optical Fiber End Face to Enhance the Signal of Localized Surface Plasmon Resonance Biosensors: A Case Study for Deoxynivalenol Detection. Sensors and Actuators B: Chemical. 2023:133380.[2].Chen C, Li X, Zhu S, Cui P, Lei H, Yan H. Detection of the alcohol fermentation process in vinegar production with a digital micro-mirror based NIR spectra set-up and chemometrics. Journal of Food Composition and Analysis. 2023;115:105036. [3].Lei H, Chen C, Yan H. A Portable Optical Fiber Tip Facet LSPR Aptasensor for Detection of Fumonisin B1. IEEE Sensors Journal. 2022;22(18):17838. [4].Chen C, Lei H, Liu N, Yan H. An Aptasensor for Ampicillin Detection in Milk by Fluorescence Resonance Energy Transfer Between Upconversion Nanoparticles and Au Nanoparticles. Food Chemistry - X. 2022:100439.[5].Wang L, Ge S, Gao C, Yan H, Wang J, Jia J, et al. One-pot synthesis of gold-copper nanoparticles mediated by silk fibroin peptides: Peroxidase-like properties and its application in antioxidant detection. Microchemical Journal. 2023;185:108250.[6].Wang F, Jia B, Song X, Dai J, Li X, Gao H, et al. Rapid Identification of Peucedanum praeruptorum Dunn and Its Adulterants by Hand-Held Near-Infrared Spectroscopy. Journal of Aoac International. 2022;105(3):928-33.[7].Wang F, Jia B, Dai J, Song X, Li X, Gao H, et al. Qualitative classification of Dendrobium huoshanense (Feng dou) using fast non-destructive hand-held near infrared spectroscopy. Journal of near Infrared Spectroscopy. 2022;30(3):147-153.[8].Xu Y, Xiong M, Yan H. A portable optical fiber biosensor for the detection of zearalenone based on the localized surface plasmon resonance. Sensors and Actuators B-Chemical. 2021;336:129752[9].Sedjoah R-CA-A, Ma Y, Xiong M, Yan H. Fast monitoring total acids and total polyphenol contents in fermentation broth of mulberry vinegar using MEMS and optical fiber near-infrared spectrometers. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy. 2021;260:119938.[10].Ashie A, Lei H, Han B, Xiong M, Yan H. Fast determination of three components in milk thistle extract with a hand-held NIR spectrometer and chemometrics tools. Infrared Physics & Technology. 2021;113: 103629.[11].Yan H, Han B, Siesler HW. Handheld Near-Infrared Spectrometers: Reality and Empty Promises. Spectroscopy. 2020;35(6):15-8.[12].Yan H, Xu Y-C, Siesler HW, Han B-X, Zhang G-Z. Hand-Held Near-Infrared Spectroscopy for Authentication of Fengdous and Quantitative Analysis of Mulberry Fruits. Frontiers in Plant Science. 2019;10:1548.[13].Yan H, Ma Y, Xiong Z, Siesler HW, Qi L, Zhang G. Quantitative Analysis of Organic Liquid Three-Component Systems: Near-Infrared Transmission versus Raman Spectroscopy, Partial Least Squares versus Classical Least Squares Regression Evaluation and Volume versus Weight Percent Concentration Units. Molecules. 2019;24(19).[14].Yan H, Siesler HW. Hand-held near-infrared spectrometers: State-of-the-art instrumentation and practical applications. NIR news. 2018;29(7):8-12.[15].Yan H, Siesler HW. Quantitative analysis of a pharmaceutical formulation: Performance comparison of different handheld near-infrared spectrometers. Journal of Pharmaceutical and Biomedical Analysis. 2018;160:179-86.[16].Yan H, Siesler HW. Identification of textiles by handheld near infrared spectroscopy: Protecting customers against product counterfeiting. Journal of near Infrared Spectroscopy. 2018;26(5):311-21.[17].Yan H, Siesler HW. Identification Performance of Different Types of Handheld Near-Infrared (NIR) Spectrometers for the Recycling of Polymer Commodities. Applied Spectroscopy. 2018;72(9):1362-70.[18].Yan H, Ma Y, Han B. Rapid detection of the component contents in caryophylli flos by a handheld near infrared spectrometer based on digital light processing technology. Journal of near Infrared Spectroscopy. 2018;26(6):389-97.   专利成果 授权发明专利[1].光纤LSPR适配体生物传感器及其制备方法和应用, CN113376120B[2].微流控纸芯片阵列及其制备方法和应用, CN108956598B. [3].一种利用荧光光谱监控酶法制备降血糖肽的方法, CN106996925B [4].一种酶解法生产降血糖肽过程的实时监控方法, CN106967785B. [5].一种快速雌雄蚕蛹分选装置及方法, CN108212822A. 科研团队 教学随笔