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刘文广 教师名称：刘文广 教师拼音名称：Liu Wenguang 出生日期：1968-03-29 性别：男 职称：教授 其他联系方式 移动电话：022-27402487 邮箱：wgliu@tju.edu.cn 基本信息 研究方向 获奖情况 论文成果 Areas of research interest1. Soft and wet biomaterials;2. Nonviral vector for gene delivery;3. Drug delivery system;4. Soft tissue engineering;5. Functional polymer materials.TeachingSoft Matter and its Medical Applications ( Undergraduate)Honors and awards1. First Class Prize of Tianjin Municipal Natural Science and Technology Award (ranked second), October 2002;2. Second Class Prize of Tianjin Municipal Natural Science and Technology Award (ranked first), October 2015 3. Outstanding Teacher Title of Tianjin University, September 2010;4. National Natural Science Funds for Distinguished Young Scholar, 2013;5. May lst Labour Medal of Tianjin , 2014.Research projects1. National Outstanding Youth Fund Project;2. General Program of National Natural Science Fund;3. Key Program of Tianjin Natural Science Fund;4. Thematic Projects of National 863 Programs.Selected publications(Journal articles, patents and books)# Dai X, Zhang Y, Gao L, Bai T, Wang W, Cui Y, et al. A Mechanically Strong, Highly Stable, Thermoplastic, and Self-Healable Supramolecular Polymer Hydrogel. Advanced Materials. 2015;27(23):3566-71. # Li Y, Xu B, Bai T, Liu W. Co-delivery of doxorubicin and tumor-suppressing p53 gene using a POSS-based star-shaped polymer for cancer therapy. Biomaterials. 2015;55:12-23. # Li Y, Yang J, Xu B, Gao F, Wang W, Liu W. Enhanced Therapeutic siRNA to Tumor Cells by a pH-Sensitive Agmatine-Chitosan Bioconjugate. ACS Applied Materials & Interfaces. 2015;7(15):8114-24. # Xu B, Li Y, Gao F, Zhai X, Sun M, Lu W, et al. High Strength Multifunctional Multiwalled Hydrogel Tubes: Ion-Triggered Shape Memory, Antibacterial, and Anti-inflammatory Efficacies. ACS Applied Materials & Interfaces. 2015;7(30):16865-72. # Zhang Y, Li Y, Liu W. Dipole-Dipole and H-Bonding Interactions Significantly Enhance the Multifaceted Mechanical Properties of Thermoresponsive Shape Memory Hydrogels. Advanced Functional Materials. 2015;25(3):471-80. # Cheng L, Li Y, Zhai X, Xu B, Cao Z, Liu W. Polycation-b-Polyzwitterion Copolymer Grafted Luminescent Carbon Dots As a Multifunctional Platform for Serum-Resistant Gene Delivery and Bioimaging. ACS Applied Materials & Interfaces. 2014;6(22):20487-97. # Wang N, Zhang J, Sun L, Wang P, Liu W. Gene-modified cell detachment on photoresponsive hydrogels strengthened through hydrogen bonding. Acta Biomaterialia. 2014;10(6):2529-38. # Wang W, Lu Y, Yue Z, Liu W, Cao Z. Ultrastable core-shell structured nanoparticles directly made from zwitterionic polymers. Chemical Communications. 2014;50(95):15030-3. # Wang W, Sun L, Zhang P, Song J, Liu W. An anti-inflammatory cell-free collagen/resveratrol scaffold for repairing osteochondral defects in rabbits. Acta Biomaterialia. 2014;10(12):4983-95. # Zhao X, Li Z, Pan H, Liu W, Lv M, Leung F, et al. Enhanced gene delivery by chitosan-disulfide-conjugated LMW-PEI for facilitating osteogenic differentiation. Acta Biomaterialia. 2013;9(5):6694-703. # Liu C, Zhang P, Zhai X, Tian F, Li W, Yang J, et al. Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence. Biomaterials. 2012;33(13):3604-13. # Luo Y, Zhai X, Ma C, Sun P, Fu Z, Liu W, et al. An inhalable 2-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung. Journal of Controlled Release. 2012;162(1):28-36. # Yang J, Liu Y, Wang H, Liu L, Wang W, Wang C, et al. The biocompatibility of fatty acid modified dextran-agmatine bioconjugate gene delivery vector. Biomaterials. 2012;33(2):604-13. # Zhai X, Zhang P, Liu C, Bai T, Li W, Dai L, et al. Highly luminescent carbon nanodots by microwave-assisted pyrolysis. Chemical Communications. 2012;48(64):7955-7. # Zhang P, Li W, Zhai X, Liu C, Dai L, Liu W. A facile and versatile approach to biocompatible "fluorescent polymers" from polymerizable carbon nanodots. Chemical Communications. 2012;48(84):10431-3. # Lei Tang, Yang Yang, Tao Bai, Wenguang Liu*. Robust MeO(2)MA/vinyl-4,6-diamino-1,3,5-triazine copolymer hydrogels-mediated reverse gene transfection and thermo-induced cell detachment. Biomaterials 2011,32:1943-1949. # Fengying Dai, Wenguang Liu*. Enhanced gene transfection and serum stability of polyplexes by PDMAEMA-polysulfobetaine diblock copolymers. Biomaterials 2011,32:628-638. # Lei Tang, Wenguang Liu*, Guipei Liu. High-strength hydrogels with integrated functions of H-bonding and thermoresponsive surface-mediated reverse transfection and cell detachment. Advanced Materials 2010, 22:2652-2656. # Fengying Dai, Peng Sun, Yongjie Liu, Wenguang Liu*. Redox-cleavable star cationic PDMAEMA by arm-first approach of ATRP as a nonviral vector for gene delivery. Biomaterials 2010, 31:559-569. # Peng Zhang, Wenguang Liu*, ZnO QD@PMAA-co-PDMAEMA nonviral vector for plasmid DNA delivery and bioimaging. Biomaterials 2010,31: 3087-3094. # Yang Jianhai, Zhang Peng, Tang Lei, Sun Peng, Liu Wenguang*, Sun Pei, Zuo Aijun, Liang Dongchun. Temperature-tuned DNA condensation and gene transfection by PEI-g-(PMEO(2)MA-b-PHEMA) copolymer-based nonviral vectors. Biomaterials 2010, 31:144-155. # McLaughlin CR, Acosta MC, Luna C, Liu WG, Belmonte C, Griffith M, Gallar J. Regeneration of functional nerves within full thickness collagen-phosphorylcholine corneal substitute implants in guinea pigs. Biomaterials 2010 31(10):2770-2778. # Merrett K, Liu WG, Mitra D, Camm KD, McLaughlin CR, Liu Y, Watsky MA, Li F, Griffith M, Fogg DE. Synthetic neoglycopolymer-recombinant human collagen hybrids as biomimetic crosslinking agents in corneal tissue engineering. Biomaterials 2009,30(29):5403-5408. # Wenguang Liu, Chao Deng, Christopher R. McLaughlin, Per Fagerholm, Neil S. Lagali, Belinda Heyne, Juan C. Scaiano, Mitchell A. Watsky, Yasuhiro Kato, Rejean Munger, Naoshi Shinozaki, Fengfu Li, May Griffith. Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes. Biomaterials 2009,30(8):1551-1559. # Ling Zhang, Wenguang Liu, Lin Lin, Dayong Chen, Martina H. Stenzel. Degradable Disulfide Core-Cross-Linked Micelles as a Drug Delivery System Prepared from Vinyl Functionalized Nucleosides via the RAFT Process. Biomacromolecules 2008,9:3321-3331. # Wenguang Liu, Kimberley Merrett, May Griffith, Per Fagerholm, Subhadra Dravida, Belinda Heyne, Juan C. Scaiano, Mitchell A. Watsky, Naoshi Shinozaki, Neil Lagali, Rejean Munger and Fengfu Li. Recombinant human collagen for tissue engineered corneal substitutes. Biomaterials 2008, 29:1147-1158. # Zhiqiang Cao, Wenguang Liu*, Dongchun Liang, Gang Guo, Jingyu Zhang. Design of Novel Poly(vinyldiaminotriazine)-based Non-viral Vectors via Specific Hydrogen Bonding with Nucleic Acid Base Pairs, Advanced Functional Materials 2007, 17:246-252.Social Appointments1. Standing committee member of Chinese Biomaterials Society Youth Committee;2. Committee member of Biomedical Polymers Branch of Chinese Biomaterials Society;3. Youth Working Committee member of. Biomedical polymer materials, functional polymer materials. 暂无内容 暂无内容 教育经历 2019.12-1991.7 Tianjin University   Polymer Chemical Engineering   学士 2019.12-1996.3 Tianjin University   Polymer Materials   硕士 2019.12-1999.4 Tianjin University   Biomedical Engineering   博士 工作经历 2004.3 -2004.11 |Institute of Textile and Clothing|The Hong Kong Polytechnic University|Research Associate 2005.3 -2006.11 |Department of Cellular & Molecular Medicine|The University of Ottawa|Postdoctoral fellow 2007.6 -2019.12 |School of Materials Science & Engineering|Tianjin University|Professor